Figure 1.

Circ‐TSPAN4 is highly expressed in LUAD. (a) The top five differentially expressed circRNAs in GEO database (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE104854) containing three pairs of LUAD and adjacent normal tissues. (b, c) qRT‐PCR analysis for circ‐TSPAN4 expression in LUAD tissues and cell lines. (d) The receiver operating characteristic (ROC) curve of circ‐TSPAN4 expression levels in metastatic versus nonmetastatic LUAD patients. (e) The overall survival curve of LUAD patients with high and low circ‐TSPAN4 expression. (f) The ROC curve of circ‐TSPAN4 expression levels in alive versus dead LUAD patients. All data are presented as mean ± SD of at least three independent experiments