Figure 1. miR-34a-5p was up-regulated in preeclamptic placenta specimens.

(A) Heatmap of normalized expression levels of miRNAs in placentas samples from three patients with PE and three women with normal pregnancies. Blue indicates low expression levels; red indicates high expression levels. (B) Real-time PCR was performed to determine the expression levels of miR-34a-5p in preeclamptic placentas (n=20) and normal pregnancies (n=20), as well as in (C) serum samples from preeclamptic placentas (n=20) and normal pregnancies (n=20). P<0.01 vs. Control group.