Table 3.
Results of DAVID Bioinformatics analysis for the comparison between sham and acquisition groups
| Functional annotation term summary* | Enrichment score | FDR (q value) | ||||
|---|---|---|---|---|---|---|
| Cluster | Median | SD | Lowest | Highest | ||
| 1 | Postsynaptic membrane | 13.96 | 5.88E-13 | 0.055 | 1.65E-20 | 0.18 |
| 2 | Synapse | 12.40 | 6.63E-12 | 0.041 | 1.65E-20 | 0.092 |
| 3 | Ion transport | 9.54 | 3.25E-07 | 4.75E-07 | 1.49E-07 | 1.05E-06 |
| 4 | Mitochondrial inner membrane | 7.44 | 0.0154 | 0.093 | 2.25E-12 | 0.19 |
| 5 | Positive regulation of excitatory postsynaptic potential | 5.23 | 0.0014 | 0.848 | 3.79E-04 | 1.47 |
| 6 | Neuronal membrane-associated guanylate kinases | 5.16 | 0.0163 | 0.224 | 4.25E-04 | 0.46 |
| 7 | PDZ and SH3 domains | 4.91 | 0.0121 | 19.78 | 1.44E-07 | 65.75 |
| 8 | Ionotropic glutamate and NMDA receptors | 4.86 | 0.0272 | 0.859 | 3.01E-04 | 1.50 |
| 9 | AMPA glutamate receptor complex | 4.42 | 0.0104 | 5.28 | 0.0018 | 9.15 |
| 10 | Glutamatergic synapses | 4.34 | 0.1636 | 25.26 | 1.44E-07 | 100.0 |
| 11 | Guanylate-kinase-associated protein | 4.25 | 1.0843 | 0.682 | 4.25E-04 | 1.26 |
*
See Extended Data Table 3-1 for detailed functional clustering annotation terms.