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. 2019 Dec 9;7(23):e14303. doi: 10.14814/phy2.14303

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© 2019 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Mitochondrial gene expression is not different between WT and LRRC8A‐KO HAP‐1 cells. NADH‐ubiquinone oxidoreductase (NDUFS) complex I (a), Succinate dehydrogenase (SDH) complex II (b), Cytochrome b (cytb) Complex III (c), Cytochrome Oxidase (MT‐CO1) complex IV (d), and mitochondrial encoded ATP synthase membrane subunit 6 (MT‐ATP6) complex V (e) levels in WT and LRRC8A‐KO cells were not significantly different. Mitochondrial DNA (f) and mitochondrial transcription factor A (TFAM) expression (g) were also not significantly different between the two groups (n = 3)