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. 2019 Jun 7;9(6):1183–1192. doi: 10.1016/j.apsb.2019.05.007

Table 1.

The kinetic parameters of different peptides towards SIRT2 and SIRT3.

Peptide SIRT2 (0.3 μmol/L)
SIRT3 (0.4 μmol/L)
Km (μmol/L) 10−3×Kcat (1/s) Kcat/Km (L/mol∙s) Km (μmol/L) 10−3×Kcat (1/s) Kcat/Km (L/mol∙s)
ne-T9 6.58±1.78 9.68±1.04 1471.12 3.49±0.47 3.98±0.18 1140.40
ne-H9 1.81±0.21 4.85±0.15 2679.56 2.92±0.47 4.91±0.25 1681.51
on-H9 2.40±0.46 7.56±0.44 3150.00 1.03±0.18 3.74±0.16 3631.17
ne-P9 14.77±3.20 1.03±1.16 69.74 0.74±0.01 0.74±0.01 317.60
ne-K9 1.05±0.17 5.00±0.20 4347.83 4.75±0.79 4.75±0.28 1000.00
ne-D9 1.48±0.24 6.63±0.28 4479.73
ne-K4a 1.98±0.26 5.85±0.22 2954.55

–Not detected.