Table 2.
Phase solubility study of ketoprofen with different CDs in distilled water at 37 ± 0.5 °C.
| System | Equation | Kca (L/mol) | R2b | ΔGc (kJ/mol) |
|---|---|---|---|---|
| KTP-α-CD | y = 0.007x + 1.157 | 6.408 | 0.578 | N/A |
| KTP-β-CD | y = 0.397x + 1.038 | 598.523 | 0.993 | −16.489 |
| KTP-γ-CD | y = 0.103x + 0.999 | 104.388 | 0.983 | −11.986 |
| KTP-Hp-β-CD | y = 0.559x + 0.744 | 1152.340 | 0.985 | −18.178 |
| KTP-DMe-β-CD | y = 0.544x + 1.046 | 1084.530 | 0.999 | −18.021 |
| KTP-SBE-β-CD | y = 0.530x + 1.423 | 1025.145 | 0.993 | −17.876 |
a
Stability constant.
b
Correlation coefficient.
c
Gibbs free energy at the temperature of 37 ± 0.5 °C.