Table 1.

Study selection and subject characteristics of included studies in meta-analysis.

Author	Yr	Ethnicity	Age	Cases	Controls	Genotypes for cases		Genotypes for controls		Genotypes for cases			Genotypes for controls			P for HWE
						G	C	G	C	GG	GC	CC	GG	GC	CC
-174G/C
Schluter	2002	Caucasian	Adult	50	276	51	49	313	239	13	25	12	91	131	54	0.58
Treszl	2003	Caucasian	Neonatal	33	70	49	17	97	43	18	13	2	34	29	7	0.82
Balding	2003	Caucasian	Adult	183	389	215	151	371	241	59	97	27	97	177	32	0.00
Ahrens	2004	Caucasian	Neonatal	50	306	69	31	57	309	24	21	5	3	51	129	0.42
Sipahi	2006	Caucasian	Pediatric	44	77	66	22	123	31	26	14	4	52	19	6	0.04
Gopel	2006	Caucasian	Neonatal	97	320	108	86	399	241	29	50	18	128	143	49	0.39
Baier #1	2006	African	Neonatal	114	119	206	22	229	9	94	18	2	110	9	0	0.67
Baier #2	2006	Caucasian	Neonatal	31	26	40	22	30	22	12	16	3	7	16	3	0.01
Michalek	2007	Caucasian	Pediatric	409	644	477	341	665	623	127	223	59	160	345	139	0.07
Abdel-Hady	2009	African	Neonatal	54	71	60	48	88	54	17	26	11	28	32	11	0.71
Davis	2010	Caucasian	Adult	23	52	31	15	64	40	10	11	2	21	22	9	0.44
Carregaro	2010	Mix	Adult	97	207	137	57	284	130	49	39	9	94	96	17	0.27
Shimada	2011	Asian	Adult	123	102	246	0	204	0	123	0	0	102	0	0	0.00
Martin-Loeches	2012	Caucasian	Adult	1227	953	1678	776	1289	617	581	516	130	438	413	102	0.75
Panayides	2015	Caucasian	Adult	185	108	303	67	184	32	123	57	5	79	26	3	0.63
Mao	2016	Asian	Adult	188	162	149	227	182	142	56	37	95	68	46	48	0.00
-572C/G
Michalek	2007	Caucasian	Pediatric	409	644	51	767	56	1228	7	37	365	2	52	588	0.46
Gu	2008	Asian	Adult	54	321	26	82	153	489	5	16	33	16	121	184	0.49
Shimada	2011	Asian	Adult	123	102	53	191	41	163	3	47	72	2	37	63	0.19
Panayides	2015	Caucasian	Adult	198	115	49	347	49	181	6	37	155	6	37	72	0.66