Table 2.

Summary ORs and 95% CIs of IL-6-174G/C polymorphism and sepsis risk.

		C vs. G	CC vs. GG	GC vs. GG	Dominant model	Recessive model
	n	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
Total	16	1.04 (0.79–1.38)	0.86 (0.53–1.41)	0.99 (0.79–1.24)	0.97 (0.74–1.29)	0.92 (0.61–1.39)
Ethnicity
Asian	2	0.51 (0.38–0.69)	2.40 (1.46–3.94)	0.94 (0.72–1.24)	1.71 (1.10–2.65)	2.43 (1.56–3.77)
Caucasian	11	1.22 (0.91–1.63)	0.66 (0.37–1.19)	0.97 (0.52–1.80)	0.84 (0.60–1.17)	0.74 (0.46–1.18)
African	2	0.61 (0.40–0.93)	1.96 (0.76–5.10)	1.75 (0.98–3.11)	1.87 (1.08–3.25)	1.63 (0.69–3.87)
Age
Adult	8	0.87 (0.69–1.09)	1.21 (0.98–1.50)	0.97 (0.84–1.11)	1.02 (0.89–1.16)	1.31 (0.91–1.88)
Neonate	6	1.29 (0.48–3.46)	0.50 (0.08–3.04)	0.79 (0.35–1.80)	0.66 (0.23–1.88)	0.66 (0.18–2.51)
Children	2	1.08 (0.65–1.81)	0.57 (0.40–0.83)	0.87 (0.66–1.14)	0.93 (0.50–1.75)	0.64 (0.46–0.88)
HWE
Yes	11	1.15 (0.82–1.61)	0.70 (0.38–1.28)	1.00 (0.75–1.34)	0.90 (0.63–1.28)	0.75 (0.46–1.21)
No	5	0.78 (0.52–1.17)	1.79 (1.25–2.57)	0.95 (0.71–1.28)	1.22 (0.93–1.58)	1.88 (1.36–2.60)
Caucasian (yes)	8	1.35 (0.89–2.03)	0.53 (0.25–1.12)	0.93 (0.65–1.31)	0.77 (0.50–1.18)	0.62 (0.35–1.09)
Caucasian (no)	3	0.93 (0.74–1.17)	1.28 (0.76–2.18)	0.94 (0.67–1.34)	1.00 (0.72–1.40)	1.38 (0.85–2.24)

HWE: Hardy–Weinberg equilibrium.