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. 2019 Oct 4;244(16):1463–1474. doi: 10.1177/1535370219881358

Figure 6.

Figure 6.

Effects of NB on VSOR Cl− currents in HT22 cells. (a) Cl− currents recorded under isosmotic solution (Ctrl), H2O2 (500 µmol/L) treatment, and H2O2 plus NB (500 µmol/L) treatment, n = 5. (b) Corresponding current voltage (I–V) relationship for the mean current densities of cells subjected to indicated treatments. (c) Current densities at +100 mV from panel b, n = 5. (d) Negligible background Cl− currents recorded under isosmotic solution (Ctrl). H2O2 (500 µM)-induced Cl− currents exhibiting representative properties of VSOR Cl− currents. H2O2-induced VSOR Cl− currents were inhibited by adding DCPIB (10 µmol/L); n =5. (E) Corresponding current–voltage (I–V) relationship for the mean current densities of cells subjected to indicated treatments. (f) Current densities at +100 mV from panel e. The data are presented as the mean ± SD of three experiments. *P < 0.05 vs. Control group. #P < 0.05 vs. H2O2 group.