Table 3.
Clinical relevance of the 3 htSNPs among trauma patients in Guizhou.
| SNPs | Genotypes | N | Age(yr) | Gender (M/F) | ISS | Sepsis, n/% | MOD score |
|---|---|---|---|---|---|---|---|
| rs1982809 | TT | 307 | 41.9±16.7 | 231/76 | 25.2±7.3 | 97 (31.6) | 5.7±2.2 |
| TC | 206 | 41.8±15.7 | 185/21 | 26.2±8.5 | 82 (39.8) | 6.8±2.6 | |
| CC | 49 | 42.1±16.2 | 40/9 | 28.2±8.3 | 28 (57.1)a1 | 7.5±2.6a2,b1,c1 | |
| AA | 294 | 42.8±11.8 | 244/50 | 27.8±7.9 | 102 (34.7) | 5.4±2.5 | |
| rs9288952 | AG | 236 | 43.5±12.3 | 190/46 | 26.1±8.2 | 93 (39.4) | 6.8±2.8 |
| GG | 32 | 43.2±16.7 | 22/10 | 25.7±9.0 | 12 (37.5) | 6.4±2.8 | |
| TT | 164 | 43.5±11.3 | 137/27 | 25.7±7.8 | 62 (37.8) | 6.5±3.2 | |
| rs9288953 | TC | 263 | 42.6±12.4 | 205/58 | 25.9±8.3 | 103 (39.2) | 6.8±2.7 |
| CC | 135 | 43.7±15.4 | 114/21 | 26.5±7.7 | 42 (31.1) | 6.0±2.3 |
a1P = 0.005, a2P = 0.011 for dominant association (CC + TC vs. TT).
b1P = 0.003 for recessive association (CC vs. TT + TC).
c1P = 0.005 for allele dose association.
ISS: injury severity score; MOD: multiple organ dysfunction; N: number; M/F: male/female; SNP: single nucleotide polyorphism.