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. 2019 Nov 21;10:1386. doi: 10.3389/fphar.2019.01386

Figure 4.

Figure 4

Effects of choline on transverse aortic constriction (TAC)-induced myocardial fibrosis. (A) Representative heart section with Masson staining in the experimental groups, scale bar: 100 μm. **p < 0.01 vs. sham, ## p < 0.01 vs. TAC, && p < 0.01 vs. choline, n = 5. (B) Effects of choline and 4-diphenylacetoxy-N-methylpiperidine methiodide (4-DAMP) on the protein level of collagen I. *p < 0.05 vs. sham, # p < 0.05 vs. TAC, & p < 0.05 vs. choline, n = 8. (C) Effects of choline and 4-DAMP on the protein level of collagen III. **p < 0.01 vs. sham, ## p < 0.01 vs. TAC, n = 8. (D) Cardiac M3 muscarinic acetylcholine receptor protein level after TAC surgery and choline or 4-DAMP treatment. *p < 0.05 vs. sham, ## p < 0.01 vs.TAC, && p < 0.01 vs. choline, n = 8.