Figure 2. Effects of amphetamine (AMPH) sensitization and N-acetylcysteine (NAC) on latent inhibition (LI). LI was observed in the control group (saline – SAL/SAL) (A), and disrupted by amphetamine (SAL/AMPH) (C). NAC abolished LI in control animals (NAC/SAL) (B) and failed to prevent amphetamine sensitization-induced disruption of LI (NAC/AMPH) (D). Mean + standard error, n=7-9. NPE = non-preexposed; PE = preexposed. * p < 0.01, concerning main effect of preexposure condition.