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Transplanted RPC form kidney in the renal-deficient fetus. (A) Genotyping of the fetus (Six2-GFPCre+; iDTR+). (B) GFP-expressing RPCs transplanted into the renal development area of the kidney-deficient embryo (Six2-GFPCre+; iDTR+) at E13.5. (C) Fetuses 6 days after transplantation. (D and E) Fetal kidney 6 days after transplantation. Note the unilateral GFP expression (right side). (F) Kidney of wild-type B6 mouse at E19.5. a, adrenal gland; k, fetal kidney; u, fetal ureter.
