Table 1.
Recipient Fetus | Survival Ratea | Rate of Donor Cells Remainingb | Rate of Including Cells inside Host Kidneyc |
---|---|---|---|
Wild-type mouse | 14 of 19 (74%) | 11 of 14 (79%) | 2 of 11 (18%) |
Six2Cre/iDTR mouse | 8 of 10 (80%) | 7 of 8 (88%) | 2 of 7 (29%) |
Living fetus/cells-implanted fetus.
Fluorescence stereomicroscopy confirmed the presence of GFP-positive cells inside the embryos.
Analysis by immunostaining confirmed the donor cells were included inside the host kidney.