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. 2019 Dec 9;8:37. doi: 10.1186/s40035-019-0178-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Brain perfusion is globally decreased in MS. Perfusion-weighted brain MRI (arterial spin labelling) from a 35-year old healthy male volunteer (left) versus a 34-year old man with relapsing-remitting MS (right), with CBF color-coded map overlay. Brain perfusion is globally reduced in the MS patients, as compared to the healthy volunteer. CBF: cerebral blood flow (expressed as mL/100 g/min), MS: multiple sclerosis, MRI: magnetic resonance imaging