Table 2.
Univariate and Multivariate Analyses of Factors Associated with Overall Survival
| Factors | OS | |||
|---|---|---|---|---|
| Univariate, P | Multivariate | |||
| HR | 95% CI | P value | ||
| Sex (Female vs. Male) | 0.372 | NA | ||
| Age (years) (≤ 60 vs. > 60) | 0.821 | NA | ||
| Smoking status (Smokers vs. Nonsmokers) | 0.117 | NA | ||
| Histological type (SCC vs. Adenocarcinomas) | 0.061 | NA | ||
| Lymph node metastasis (Yes vs. No) | 0.026 | NS | ||
| Differentiation (Well and moderate vs. Poor) | 0.014 | NS | ||
| Tumor size (diameter, cm) (> 3 vs. ≤ 3) | 0.007 | 1.417 | 1.094–2.217 | 0.031 |
| TNM (III-IV vs. I-II) | 0.056 | NA | ||
| CircFGFR1 expression (High vs. Low) | 0.002 | 1.574 | 0.911–1.927 | 0.013 |
OS Overall survival, NA Not adopted, NS Not significantly, SCC Squamous cell carcinoma, 95%CI 95% confidence interval, HR Hazard ratio; Cox proportional hazards regression model