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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2019 Apr 2;14(3):462–477. doi: 10.1007/s11481-019-09842-5

Fig. 2. Resveratrol alters immune cell distribution and activation in the brains of EAE mice.

Fig. 2

Infiltrating mononuclear cells were isolated from brains of VEH- or RES-treated EAE mice and stained for the indicated cell surface markers and analyzed by flow cytometry. Representative histograms and bar graphs of combined experiments (n > 3) displayed as percent positive cells of A) CD4 and B) CD11b. C) Absolute cell numbers of T cell co-stimulatory molecule CD28 and activation marker CD69 and D) co-stimulatory molecules CD80 and CD86. E) Representative dot plots of CD11b+/CD45hi and CDllb+/CD45lo mononuclear cells and bar graphs of combined experiments (n > 3). Data is presented as the mean ± S.E.M. Statistical significance (A-D) evaluated using Student’s T test or (E) One-way ANOVA with Tukey’s multiple comparisons: *, p < 0.05; ** p < 0.01; ***, p < 0.001; ****, p < 0.0001