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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2019 Apr 2;14(3):462–477. doi: 10.1007/s11481-019-09842-5

Fig. 3. Resveratrol induces apoptosis in brain-infiltrating cells.

Fig. 3

Brain-derived mononuclear cells from VEH- or RES-treated EAE mice were stained with a PI/Rnase solution and cell cycle analysis evaluated using flow cytometry. A) Flow cytometry data from a representative experiment was analyzed and stages of the cell cycle modeled using MODFit LT software. Inset, percentage of cells in stages of cell cycle displayed as pie charts, data are representative. C) Percentage of cells in stages of cell cycle and D) apoptotic cells as indicated by ModFit LT analysis from combined experiments (n > 3). Data represented as the mean ± S.E.M. Significance evaluated using Student’s T test: **, p < 0.01; ***, p < 0.001; ****, p < 0.0001