. 2019 Nov 27;2019:5340290. doi: 10.1155/2019/5340290

Table 1.

Profiling hematopoietic stem/progenitor cells in bone marrow and splenic cells.

Bone marrow cells	Days	0 Gy	5 Gy	5 Gy+IMD-0354
Bone marrow cells	Days	Cell counts (×10⁶ cells)
Population enriched with hematopoietic stem/progenitor cells	Day 7	0.10 ± 0.03	0.01 ± 0.00	0.01 ± 0.00
	Day 30	ND	0.11 ± 0.01	0.17 ± 0.01^b
Multipotent progenitor	Day 7	0.11 ± 0.04	0.01 ± 0.00	0.01 ± 0.01
Multipotent progenitor	Day 30	ND	0.11 ± 0.01	0.17 ± 0.01^b
Common myeloid-erythroid progenitor	Day 7	0.17 ± 0.04	0.01 ± 0.00	0.01 ± 0.01
Common myeloid-erythroid progenitor	Day 30	ND	0.17 ± 0.06	0.15 ± 0.06
Common lymphoid progenitor	Day 7	0.03 ± 0.00	0.01 ± 0.00	0.01 ± 0.00
Common lymphoid progenitor	Day 30	ND	0.05 ± 0.01	0.04 ± 0.02

Splenic cells	Days	0 Gy	5 Gy	5 Gy+IMD-0354
Population enriched with hematopoietic stem/progenitor cells	Day 7	0.24 ± 0.01	0.01 ± 0.00	0.01 ± 0.01
	Day 30	ND	0.13 ± 0.05	0.33 ± 0.08^a
Multipotent progenitor	Day 7	0.24 ± 0.02	0.01 ± 0.00	0.01 ± 0.01
Multipotent progenitor	Day 30	ND	0.18 ± 0.13	0.32 ± 0.08
Common myeloid-erythroid progenitor	Day 7	0.01 ± 0.02	0.00 ± 0.00	0.00 ± 0.00
Common myeloid-erythroid progenitor	Day 30	ND	0.05 ± 0.02	0.06 ± 0.01
Common lymphoid progenitor	Day 7	0.26 ± 0.00	0.04 ± 0.01	0.03 ± 0.01
Common lymphoid progenitor	Day 30	ND	0.38 ± 0.08	0.74 ± 0.06^b

Each cell population was classified according to the following surface antigens. Population enriched with hematopoietic stem/progenitor cells: Lin^– c-kit⁺ Sca-1⁺ CD34^–; multipotent progenitor: Lin^– c-kit⁺ Sca-1⁺ CD34⁺; common myeloid-erythroid progenitor: Lin^– c-kit⁺ Sca-1^– CD34⁺; common lymphoid progenitor: Lin^– c-kit^– Sca-1⁺ CD34⁺. The data are expressed as the means ± SD, and statistical significance was determined by a comparison of each group (^aP < 0.05vs. 5 Gy cohort; ^bP < 0.01vs. 5 Gy cohort). ND: no data.