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. 2019 Oct 30;5(10):FSO423. doi: 10.2144/fsoa-2019-0066

Figure 6. . The differentiation into mature macrophages differentiated in the presence of the poly(acrylic acid)-coated iron oxide nanoparticles exhibits increased levels of IL-6 and IL-8 regardless of the exposure to the magnetic field.

Figure 6. 

MDMs were differentiated in the absence (open circles) or presence (filled circles) of PAC-IONs for 5 days and nonexposed or exposed to a 1.5-T MF (MF- and MF+, respectively) for 10 min. The levels of cytokines were evaluated by CBA in supernatants of cultures (A–F). The comparisons were made with a two-way ANOVA.

n = 5 independent experiments with three replicates each.

ANOVA: Analysis of variance; CBA: Cytometric bead array; MDM: Differentiation into mature macrophage; MF: Magnetic field; PAC-ION: Poly(acrylic acid)-coated iron oxide nanoparticle.