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Effects of CX3CR1-deficiency on levels of MMP9 RNA in the whole brains of PS1-APP mice. RNA was extracted from brains of PS1-APP, WT, PS1-APP-CX3CR1+/−, and CX3CR1+/− mice and assessed for expression of MMP9 by qPCR. Data are expressed as mean percent of appropriate control ± SEM (n = 6 per genotype). * represent statistically significant.
