Table 2.
Top five association results for single variant analysis of antisocial personality scores, DSM-5 AUD symptom counts, and AUD/ASP interaction term
| Phenotype | SNP ID | Position | Gene | Major allele | Minor allele | MAF | p1 | p2 | p3 |
| ASP | rs11941860 | 46082178 | GABRG1 | C | T | .12702 | .001301 | .002412 | .003635 |
| rs11943173 | 46201185 | Intergenic | C | A | .02484 | .001573 | .002891 | .003142 | |
| rs17536746 | 46083155 | GABRG1 | C | T | .25780 | .001812 | .003061 | .004985 | |
| rs113560540 | 46230438 | Intergenic | C | T | .02453 | .003177 | .005630 | .005956 | |
| rs113446215 | 46266250 | GABRA2 | G | A | .02453 | .003177 | .005630 | .005956 | |
| DSM-5 | rs3756007 | 46391064 | GABRA2 | T | C | .06180 | .002516 | .004857 | .004194 |
| AUD | rs17537359 | 46341106 | GABRA2 | T | C | .05807 | .006838 | .013080 | .009906 |
| rs4645196 | 46657829 | Intergenic | T | C | .25776 | .007122 | .012970 | .004883 | |
| rs78659165 | 46336973 | GABRA2 | G | T | .05807 | .009465 | .01767 | .013370 | |
| rs79210378 | 46321843 | GABRA2 | G | T | .05652 | .010340 | .020450 | .015140 | |
| AUD/ASP interaction term | rs536599 | 46198934 | Intergenic | G | T | .43758 | .002877 | .017240 | .011200 |
| rs2119183 | 46272806 | GABRA2 | G | A | .10124 | .003226 | .005000 | .001370 | |
| rs497430 | 46195511 | Intergenic | T | A | .43789 | .003288 | .019000 | .011800 | |
| rs552538 | 46230846 | Intergenic | G | A | .42950 | .003644 | .020000 | .012000 | |
| rs492961 | 46228960 | Intergenic | A | G | .42857 | .003728 | .021000 | .012670 |
Notes: DSM-5 = Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; AUD = alcohol use disorder; ASP = antisocial practices; MAF = minor allele frequency. p1 = no rare variant covariate; p2 = rare variant directional covariate; p3 = rare variant direction and magnitude covariate (weighted).