Table 1.
GI50 Values Calculated from MTT Assay (72 Hrs) of Naked and Encapsulated Forms of 5F 203 and Phortress. GI50 Is Mean ± SD from Three Independent Trials, Where N = 4
| Cells Line | Test Agent | ||||
|---|---|---|---|---|---|
| 5F 203 | AFt-5F 203 | Phortress | AFt- Phortress | ||
| GI50 ± SD (µM) | MCF-7 | 0.005 ± 0.0006 | 0.033 ± 0.009 | 0.085 ± 0.017 | 0.063 ± 0.030 |
| MDA-468 | 0.014 ± 0.007 | 0.008 ± 0.008 | 0.11 ± 0.013 | 0.11 ± 0.035 | |
| TK-10 | 0.11 ± 0.09 | 0.028 ± 0.004 | 6.3 ± 2.9 | 0.098 ± 0.008 | |
| IGROV-1 | 12.8 ± 10.2 | 0.039 ± 0.011 | 0.17 ± 0.070 | 0.058 ± 0.022 | |
| HCT-116 | >50 | >0.61 | >50 | 0.14 ± 0.059 | |
| MRC-5 | >50 | >0.61 | >50 | >2.5 | |