Table 3. Activation in data-driven regions of interest.
Region | MNI coordinates x, y, z | Cluster size | Mean activation | p-Value | |
---|---|---|---|---|---|
(number of voxels) | T1D | Control | |||
All regions | — | — | 0.12 ± 0.13 | 0.11 ± 0.10 | 0.010 |
Left DLPFC | −33, 42, 23 | 1,516 | 0.11 ± 0.19 | 0.08 ± 0.18 | 0.175 |
Right DLPFC | 36, 44, 22 | 2,394 | 0.14 ± 0.22 | 0.10 ± 0.15 | 0.273 |
Left supramarginal gyrus | −58, −46, 26 | 2,918 | 0.12 ± 0.15 | 0.08 ± 0.11 | 0.061 |
Right supramarginal gyrus | 54, −38, 22 | 6,290 | 0.13 ± 0.17 | 0.07 ± 0.13 | 0.111 |
Left anterior insula and inferior frontal cortex | −32, 13, −3 | 4,316 | 0.11 ± 0.14 | 0.13 ± 0.12 | 0.122 |
Right anterior insula, inferior frontal cortex, and dorsal anterior cingulate cortex | 21, 11, 18 | 15,439 | 0.11 ± 0.13 | 0.12 ± 0.11 | 0.678 |
Left primary visual cortex | −10, −79, 5 | 658 | 0.05 ± 0.19 | 0.08 ± 0.18 | 0.175 |
Left cerebellum | −32, −56, −3 | 1,067 | 0.07 ± 0.16 | 0.06 ± 0.15 | 0.772 |
Activation values indicate raw percent signal change (mean ± standard deviation) during the contrast of no-go > go, in data-driven executive control regions of interest.
DLPFC, dorsolateral prefrontal cortex; MNI, Montreal Neurological Institute; T1D, type 1 diabetes.