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. 2019 Nov 25;17(11):e3000434. doi: 10.1371/journal.pbio.3000434

Fig 8. Frequent overexpression of GPCRs in tumors does not correlate with frequency of mutation.

Fig 8

(A) The number of tumors with GPCR mutations and of tumor types/subtypes in which the same GPCR is overexpressed for the 10 most frequently mutated GPCRs in TCGA tumors surveyed and the 10 most frequently overexpressed GPCRs. (B) The frequency of overexpression compared to the frequency of mutations. Numerical values used to generate panels A and B can be found at https://insellab.github.io/data. GPCR, G protein-coupled receptor; TCGA, The Cancer Genome Atlas.