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Examining the effect of P−5 (N-Me)Ala and P5 middle anchor residues. Superimposition of the HLA-B*0801E76C–bound 14-mers (RA)3AAKKGYCL (lime) and (R(N-Me)A)(RA)2AAKKKYCL (magenta). The two peptides bind in a nearly identical manner and share very similar structural features. The peptide residue positions (P) are indicated.
