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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Exp Neurol. 2019 Oct 31;323:113088. doi: 10.1016/j.expneurol.2019.113088

Figure 3. VTN−/− female, but not male, mice have enhanced MCAO-induced SVZ neurogenesis.

Figure 3.

Unbiased stereological counts of BrdU+ nuclei were expressed as a percentage of sham operated VTN+/+ mice. This showed that the MCAO-induced proliferation in the SVZ occurred both in females (A) and male (B), but that only female VTN−/− mice had an even greater response. BrdU+/DCX+ cell counts in the SVZ of females (C) and males (D) confirmed that this was also true for neurogenesis. N = 4, 7, 4 and 4 mice in females and N = 5, 3, 7 and 3 in males. * p<0.05, ** p<0.01, **** p<0.0001, Sham vs. MCAO, # p<0.05, VTN+/+ vs. VTN−/− in MCAO mice (Two-way ANOVA followed by post hoc Tukey multiple comparisons).