HIV-specific (tetramer+) CD8+ T cell memory subpopulations defined using CD45RA, CD27, and CCR7 during acute (14 to 36 days after diagnosis) and chronic (more that 250 days after diagnosis) infection. (a) Representative flow plots for a Fiebig I treated subject and aggregate data for the frequencies of the three memory subsets in 5 Tx Fiebig I-II treated subjects, (b) Representative flow plots for a Fiebig III treated subject and aggregate data for the frequencies of the three memory subsets in 5 Tx Fiebig III-V treated subjects, (c) Representative flow plots for one untreated subject and aggregate data for the frequencies of the three memory subsets in 4 UnTx subjects. The whiskers represents minimum and maximum values, P values were adjusted using Bonferroni-Dunn method.