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. 2019 Dec 9;9:18581. doi: 10.1038/s41598-019-54906-4

Table 4.

Univariable Cox regression analysis of the single components used in composite scores.

Univariable Model
HR p 95% CI
Cause Specific Survival ALI
Albumin (<35 g/L) 4.12 0.067 0.90 18.50
BMI (<26 kg/m2) 1.16 0.782 0.40 3.34
NLR (>3.4) 3.62 0.046 1.02 12.84
CFS
CRP (>0.3 mg/L) 4.85 0.042 1.06 22.14
Fibrinogen (>452 mg/dL) 5.73 0.003 1.82 18.14
GPS
CRP (>1 mg/dL) 1.81 0.329 0.54 6.04
Albumin (<35 g/L)
HS-mGPS
Albumin (<35 g/L)
CRP (>0.3 mg/L)
TET-aGPS
CRP (>0.3 mg/L)
Albumin (<44.4 g/L) 3.00 0.156 0.65 13.71
SII
Absolute neutrophil  count (<4.2) 1.69 0.412 0.47 6.02
 Platelet count (<266 G/L) 1.50 0.503 0.45 4.99
Absolute lymphocyte count (<1.9) 9.75 0.031 1.23 77.0
Freedom From Recurrence ALI
Albumin (<35 g/L) 3.91 0.028 1.15 13.2
BMI (<26.1 kg/m2) 1.63 0.235 0.72 3.66
NLR (>3.4) 2.59 0.043 1.02 6.54
CFS
CRP (>0.3 mg/dL) 3.53 0.013 1.30 9.57
Fibrinogen (>452 mg/dL) 4.38 0.001 1.04 5.42
GPS
CRP (>1.0 mg/dL) 2.29 0.052 0.99 5.29
Albumin (<35 g/L)
HS-GPS
Albumin (<35 g/L)
CRP (>0.3 mg/dL)
TET-aGPS
CRP (>0.3 mg/dL)
Albumin <44.4 g/L) 4.38 0.001 1.04 5.42
SII
Neutrophil count  (<4.2) 1.30 0.559 0.53 3.21
 Platelet count (<266 G/l) 1.43 0.411 0.60 3.38
Lymphocyte count (<1.9) 4.36 0.009 1.44 13.16

ALI advanced lung cancer inflammation index, CFS CRP/Fibrinogen Prognostic score, GPS Glasgow Prognostic Score, HS-mGPS the high-sensitivity modified Glasgow Prognostic Score, TET-aGPS thymic epithelial tumor adapted Glasgow Prognostic Score, SII systemic immune-inflammation index, 95% CI 95% Confidence interval, NLR neutrophil lymphocyte ratio, BMI body mass index, Neutrophil count Absolute neutrophil count, Lymphocyte count absolute Lymphocyte count.