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. 2019 Dec 9;9:18651. doi: 10.1038/s41598-019-55095-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cell Density in the Prefrontal Cortex and Ventral Striatum. (A) Cell density was significantly decreased in the OFC of Alcohol group rats compared to Naïve but not Maltodextrin. (B) Cell density was decreased in the mPFC of the Alcohol group compared to Naïve and Maltodextrin. (C) Cell density was decreased in the motor cortex of Alcohol group compared to Maltodextrin, but not Naive rats. (D) Cell density significantly decreased in the sensory cortex of Alcohol group rats compared to Naïve but not Maltodextrin. In the striatum, there were no difference between groups within either the dorsal (E) or ventral (F) regions. *p < 0.05, **p < 0.01, all error bars indicate SEM. n=6 per group.