Fig. 4.

Extrasynaptic GluN1-immunogold labeling in dendritic shafts in PL-PFC adult mice receiving vehicle or ∆9-THC during adolescence. The gold particles are located on the plasma membrane (circles) and in the cytoplasm (small arrows) of dendritic shafts (GluN1-De) having small (a, b), medium (c, d), and large (e, f) mean diameters. Many of these dendrites are opposed to glial processes (profiles outlined with dashed line) and to unlabeled (Un-Te) or GluN1-immunogold-labeled terminals (GluN1-Te) forming asymmetric synapses (curved arrows) on nearby dendritic spines. Scale bar = 500 nm