Table 4.
Gene gain and/or loss leading to human genotype.
| Gene | Human/Pig genotype, N (%) | Most plausible scenario leading to human genotype | ||||
|---|---|---|---|---|---|---|
| +/+ | +/− | −/+ | −/− | Presence through gain | Absence through loss | |
| tet(K) | 61 (84%) | 0 (0%) | 12 (16%) | 0 (0%) | 0/61 (0) | 12/12 (100) |
| erm(B) | 1 (1%) | 0 (0%) | 17 (23%) | 55 (75%) | 0/1 (0) | 17/72 (24) |
| lnu(B) | 52 (71%) | 0 (0%) | 11 (15%) | 10 (14%) | 0/52 (0) | 11/21 (52) |
| czrC | 66 (90%) | 0 (0%) | 7 (10%) | 0 (0%) | 0/66 (0) | 7/7 (100) |
| scn (IEC) | 0 (0%) | 7 (10%) | 0 (0%) | 66 (90%) | 7/7 (100) | 0/66 (0) |
The presence (+) or absence (−) of each gene in a human isolate (n = 73) was compared to the presence or absence of the gene in the most closely related isolate from pigs (n = 183). The proportion of human isolates which had acquired (Presence through gain) or lost (Absence through loss) the gene was calculated in all human isolates which displayed a different genotype than the most closely related pig isolate. The predominant scenario leading to the conclusion is highlighted in bold.