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. 2019 Dec 9;9:17638. doi: 10.1038/s41598-019-53884-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Clinical applications of osteogenic nanofibrous coating and its mechanism of action. (A) Our invention will be relevant for coating titanium implants of various geometries (e.g. bone screws, dental implants with cylindrical/conical/straight/hybrid design etc.) (B) Osteogenic nanofibrous coated titanium dental implant placed in the edentulous region of mandible (C) Autocrine and paracrine signaling of MSCs in the peri-implant zone by virtue of our nanofibrous coating will result in enhanced regeneration of bone and better osseointegration of implants.