Table 6.
Youden’s index, accuracy, positive and negative likelihood ratio (LR+ and LR−) and diagnostic odds ratio (DOR) of each discrimination index for differential βTT (n = 537) from IDA (n = 370) in patients with microcytic anemia with their 95% exact confidence interval.
| Discriminant Formula | Youden’s Index (%) | Accuracy (%) | LR + (%) | LR − (%) | DOR (%) |
|---|---|---|---|---|---|
| England and Fraser (E&F) |
48.35 (40.09–55.88) |
72.11 (69.06–75) |
4.31 (3.34–5.56) |
0.43 (0.39–0.49) |
10.02 (7.092–13.93) |
| RBC |
48.35 (39.92–56.17) |
76.59 (73.68–79.32) |
2.27 (1.98–2.60) |
0.22 (0.17–0.28) |
10.32 (7.47–14.33) |
| Mentzer |
67.66 (60.17–74.25) |
84.78 (82.28–87.06) |
4.17 (3.42–5.08) |
0.14 (0.11–0.18) |
29.79 (20.67–43.09) |
| Srivastava |
55.67 (47.39–63.17) |
77.29 (74.42–79.98) |
3.90 (3.15–4.84) |
0.31 (0.27–0.36) |
12.58 (9.07–17.34) |
| Shine and Lal (S&L) |
17.57 (12.80–21.83) |
66.37 (63.19–69.44) |
1.21 (1.16–1.27) |
0 | ∞ |
| Bessman |
–13.67 (–20.02–7.31) |
36.38 (33.25–39.61) |
0.32 (0.22–0.46) |
1.17 (1.11–1.24) |
0.27 (0.18–0.42) |
| Ricerca |
5.72 (1.97–9.60) |
61.30 (58.04–64.48) |
1.06 (1.03–1.09) |
0.19 (0.08–0.42) |
5.58 (2.46–13.33) |
| Green and King (G&K) |
65.24 (57.53–72.08) |
83.35 (80.76–85.72) |
4.06 (3.33–4.95) |
0.17 (0.14–0.21) |
23.88 (16.74–33.80) |
| Das Gupta |
31.56 (24.52–38.31) |
71.22 (68.16–74.15) |
1.49 (1.38–1.62) |
0.13 (0.09–0.19) |
11.46 (7.38–18.31) |
| Jayabose (RDWI) |
56.87 (49.20–63.83) |
81.04 (78.33–83.54) |
2.59 (2.26–2.98) |
0.12 (0.09–0.16) |
21.58 (15.23–32.96) |
| Telmissani – MCHD |
1.83 (–1.27–5.16) |
59.65 (56.37–62.86) |
1.02 (1.00–1.04) |
0.48 (0.21–1.10) |
2.13 (0.90–5.05) |
| Telmissani – MDHL |
42.10 (33.80–49.75) |
68.36 (65.22–71.37) |
3.94 (3.04–5.11) |
0.51 (0.46–0.56) |
7.73 (5.53–10.85) |
| Huber – Herklotz |
8.48 (1.05–15.63) |
48.40 (45.10–51.71) |
1.60 (1.19–2.16) |
0.90 (0.85–0.96) |
1.78 (1.25–2.54) |
| Kerman I |
56.30 (48.85–63.06) |
81.15 (78.45–83.64) |
2.48 (2.17–2.83) |
0.09 (0.06–0.13) |
27.56 (17.97–41.94) |
| Kerman II |
70.80 (63.52–77.13) |
86.00 (83.57–88.19) |
4.97 (3.98–6.20) |
0.14 (0.11–0.18) |
35.50 (24.66–52.38) |
| Sirdah |
68.91 (61.61–75.24) |
83.68 (81.11–86.03) |
7.07 (5.30–9.43) |
0.22 (0.19–0.27) |
32.14 (21.60–46.67) |
| Ehsani |
70.36 (63.06–76.72) |
85.89 (83.45–88.09) |
4.77 (3.85–5.92) |
0.14 (0.11–0.17) |
34.07 (24.26–51.49) |
| Keikhaei |
61.34 (53.51–68.38) |
82.14 (79.49–84.58) |
3.25 (2.74–3.85) |
0.16 (0.12–0.20) |
20.31 (14.63–29.53) |
| Nishad |
62.32 (54.40–69.39) |
81.92 (79.26–84.37) |
3.71 (3.07–4.49) |
0.19 (0.15–0.24) |
19.53 (13.83–27.31) |
| Wongprachum |
57.36 (49.32–64.65) |
80.38 (77.64–82.91) |
2.88 (2.46–3.37) |
0.17 (0.14–0.22) |
16.94 (11.75–23.22) |
| Sehgal |
60.68 (53.57–67.03) |
83.24 (80.65–85.62) |
2.71 (2.36–3.12) |
0.06 (0.04–0.09) |
45.17 (27.59–72.85) |
| Pornprasert |
–43.57 (–51.80 – –34.78) |
26.79 (23.93–29.80) |
0.32 (0.27–0.38) |
2.21 (1.92–2.55) |
0.15 (0.11–0.20) |
| Sirachainan |
10.80 (2–19.37) |
51.82 (48.51–55.12) |
1.43 (1.16–1.76) |
0.86 (0.78–0.93) |
1.66 (1.25–2.24) |
| Bordbar |
52.61 (45.61–58.97) |
80.15 (77.41–82.70) |
2.18 (1.94–2.44) |
0.05 (0.03–0.08) |
43.60 (24.88–75.14) |
| Matos and Carvalho |
58.04 (49.85–65.44) |
78.94 (76.14–81.55) |
3.83 (3.12–4.70) |
0.27 (0.23–0.32) |
14.20 (10.25–19.66) |
| Janel (11T) |
68.50 (61.24–74.79) |
83.24 (80.65–85.62) |
7.67 (5.66–10.40) |
0.24 (0.20–0.28) |
31.96 (21.86–48.09) |
| CRUISE |
49.34 (40.69–57.33) |
75.08 (72.13–77.87) |
2.79 (2.35–3.31) |
0.32 (0.27–0.38) |
8.72 (6.46–11.86) |
| Index26 |
71.93 (65.13–77.69) |
84.67 (82.16–86.96) |
11.24 (7.74–16.32) |
0.23 (0.19–0.27) |
48.87 (31.67–77.81) |