Table 1.
Secretome of mouse calvariae.
| Protein Accession | Gene Name |
Protein Description | MW [kDa] |
Protein Score |
# Signif. Matches |
# Unique Peptides |
Sequence Coverage | Bone-CM1* | Bone-CM2* |
|---|---|---|---|---|---|---|---|---|---|
| Other Secreted Factors | |||||||||
| IGF family | |||||||||
| [IGF2_MOUSE] | Igf2 | Insulin-like growth factor II OS = Mus musculus GN = Igf2 PE = 1 SV = 1 | 20.0 | 113.83 | 4 | 2 | 12.78 | yes | yes |
| TGF family | |||||||||
| [TGFB1_MOUSE] | Tgfb1 | Transforming growth factor beta-1 OS = Mus musculus GN = Tgfb1 PE = 1 SV = 1 | 44.3 | 31.51 | 1 | 1 | 5.13 | yes | |
| Growth Factors | |||||||||
| [FETUA_MOUSE] | Ahsg | Alpha-2-HS-glycoprotein OS = Mus musculus GN = Ahsg PE = 1 SV = 1 | 37.3 | 252.56 | 7 | 4 | 15.94 | yes | |
| [DKK3_MOUSE] | Dkk3 | Dickkopf-related protein 3 OS = Mus musculus GN = Dkk3 PE = 2 SV = 1 | 38.4 | 136.07 | 2 | 2 | 10.60 | yes | |
| [NGAL_MOUSE] | Lcn2 | Neutrophil gelatinase-associated lipocalin OS = Mus musculus GN = Lcn2 PE = 1 SV = 1 | 22.9 | 128.01 | 4 | 3 | 16.50 | yes | |
| [FSTL1_MOUSE] | Fstl1 | Follistatin-related protein 1 OS = Mus musculus GN = Fstl1 PE = 1 SV = 2 | 34.5 | 113.85 | 3 | 3 | 11.76 | yes | yes |
| [NPTX1_MOUSE] | Nptx1 | Neuronal pentraxin-1 OS = Mus musculus GN = Nptx1 PE = 2 SV = 1 | 47.1 | 68.33 | 1 | 1 | 5.09 | yes | |
| [VASN_MOUSE] | Vasn | Vasorin OS = Mus musculus GN = Vasn PE = 2 SV = 2 | 72.2 | 65.32 | 2 | 2 | 7.88 | yes | |
| [MIA_MOUSE] | Mia | Melanoma-derived growth regulatory protein OS = Mus musculus GN = Mia PE = 2 SV = 2 | 14.6 | 34.91 | 1 | 1 | 6.92 | yes | yes |
| [NEO1_MOUSE] | Neo1 | Neogenin OS = Mus musculus GN = Neo1 PE = 1 SV = 1 | 163.1 | 31.17 | 1 | 1 | 1.21 | yes | |
| [LECT1_MOUSE] | Lect1 | Leukocyte cell-derived chemotaxin 1 OS = Mus musculus GN = Lect1 PE = 1 SV = 2 | 37.2 | 26.23 | 1 | 1 | 2.10 | yes | |
| Cytokines | |||||||||
| [CSF1_MOUSE] | Csf1 | Macrophage colony-stimulating factor 1 OS = Mus musculus GN = Csf1 PE = 1 SV = 2 | 60.6 | 72.58 | 1 | 1 | 2.54 | yes | yes |
| [MIF_MOUSE] | Mif | Macrophage migration inhibitory factor OS = Mus musculus GN = Mif PE = 1 SV = 2 | 12.5 | 71.44 | 1 | 1 | 9.57 | yes | yes |
| Chemokines | |||||||||
| [S10A9_MOUSE] | S100a9 | Protein S100-A9 OS = Mus musculus GN = S100a9 PE = 1 SV = 3 | 13.0 | 184.25 | 8 | 4 | 38.94 | yes | |
| [S10AA_MOUSE] | S100a10 | Protein S100-A10 OS = Mus musculus GN = S100a10 PE = 1 SV = 2 | 11.2 | 163.77 | 6 | 3 | 49.48 | yes | yes |
| [S10A8_MOUSE] | S100a8 | Protein S100-A8 OS = Mus musculus GN = S100a8 PE = 1 SV = 3 | 10.3 | 140.97 | 7 | 2 | 50.56 | yes | yes |
| [S10AD_MOUSE] | S100a13 | Protein S100-A13 OS = Mus musculus GN = S100a13 PE = 1 SV = 1 | 11.2 | 96.16 | 2 | 2 | 23.47 | yes | |
| [S10AB_MOUSE] | S100a11 | Protein S100-A11 OS = Mus musculus GN = S100a11 PE = 1 SV = 1 | 11.1 | 74.64 | 3 | 1 | 16.33 | yes | yes |
| [S10A6_MOUSE] | S100a6 | Protein S100-A6 OS = Mus musculus GN = S100a6 PE = 1 SV = 3 | 10.0 | 46.38 | 1 | 1 | 8.99 | yes | |
| Others | |||||||||
| [NUCB1_MOUSE] | Nucb1 | Nucleobindin-1 OS = Mus musculus GN = Nucb1 PE = 1 SV = 2 | 53.4 | 506.84 | 12 | 9 | 24.84 | yes | yes |
| [CALU_MOUSE] | Calu | Calumenin OS = Mus musculus GN = Calu PE = 1 SV = 1 | 37.0 | 337.55 | 7 | 6 | 31.75 | yes | yes |
| [CH3L1_MOUSE] | Chi3l1 | Chitinase-3-like protein 1 OS = Mus musculus GN = Chi3l1 PE = 1 SV = 3 | 43.9 | 327.84 | 11 | 6 | 21.08 | yes | |
| [PPBT_MOUSE] | Alpl | Alkaline phosphatase OS = Mus musculus GN = Alpl PE = 1 SV = 2 | 57.5 | 299.32 | 6 | 5 | 15.27 | yes | yes |
| [CLUS_MOUSE] | Clu | Clusterin OS = Mus musculus GN = Clu PE = 1 SV = 1 | 51.6 | 193.06 | 5 | 4 | 10.94 | yes | |
| [OLFL3_MOUSE] | Olfml3 | Olfactomedin-like protein 3 OS = Mus musculus GN = Olfml3 PE = 2 SV = 2 | 45.7 | 158.37 | 3 | 3 | 7.88 | yes | yes |
| [NGP_MOUSE] | Ngp | Neutrophilic granule protein OS = Mus musculus GN = Ngp PE = 1 SV = 1 | 19.3 | 83.71 | 1 | 1 | 12.57 | yes | |
| [UCMA_MOUSE] | Ucma | Unique cartilage matrix-associated protein OS = Mus musculus GN = Ucma PE = 1 SV = 1 | 16.6 | 76.49 | 1 | 1 | 9.42 | yes | yes |
| [SAP_MOUSE] | Psap | Prosaposin OS = Mus musculus GN = Psap PE = 1 SV = 2 | 61.4 | 69.91 | 3 | 1 | 3.59 | yes | yes |
| [CCD80_MOUSE] | Ccdc80 | Coiled-coil domain-containing protein 80 OS = Mus musculus GN = Ccdc80 PE = 1 SV = 2 | 107.5 | 60.21 | 1 | 1 | 1.26 | yes | |
| [DAG1_MOUSE] | Dag1 | Dystroglycan OS = Mus musculus GN = Dag1 PE = 1 SV = 4 | 96.8 | 57.62 | 1 | 1 | 1.79 | yes | |
| [CRTAP_MOUSE] | Crtap | Cartilage-associated protein OS = Mus musculus GN = Crtap PE = 1 SV = 3 | 46.1 | 51.66 | 1 | 1 | 2.75 | yes | |
| [CDSN_MOUSE] | Cdsn | Corneodesmosin OS = Mus musculus GN = Cdsn PE = 2 SV = 2 | 54.3 | 36.81 | 1 | 1 | 3.21 | yes | |
| Matrisome Core Proteins | |||||||||
| ECM-Glycoproteins | |||||||||
| [FINC_MOUSE] | Fn1 | Fibronectin OS = Mus musculus GN = Fn1 PE = 1 SV = 4 | 272.4 | 3888.07 | 171 | 66 | 40.09 | yes | yes |
| [TENA_MOUSE] | Tnc | Tenascin OS = Mus musculus GN = Tnc PE = 1 SV = 1 | 231.7 | 2310.24 | 56 | 39 | 27.20 | yes | yes |
| [TENN_MOUSE] | Tnn | Tenascin-N OS = Mus musculus GN = Tnn PE = 1 SV = 2 | 173.0 | 2200.77 | 61 | 37 | 38.40 | yes | yes |
| [POSTN_MOUSE] | Postn | Periostin OS = Mus musculus GN = Postn PE = 1 SV = 2 | 93.1 | 1000.50 | 33 | 19 | 30.43 | yes | yes |
| [BGH3_MOUSE] | Tgfbi | Transforming growth factor-beta-induced protein ig-h3 OS = Mus musculus GN = Tgfbi PE = 1 SV = 1 | 74.5 | 703.94 | 25 | 12 | 23.87 | yes | yes |
| [OSTP_MOUSE] | Spp1 | Osteopontin OS = Mus musculus GN = Spp1 PE = 1 SV = 1 | 32.4 | 669.32 | 19 | 10 | 44.90 | yes | yes |
| [AEBP1_MOUSE] | Aebp1 | Adipocyte enhancer-binding protein 1 OS = Mus musculus GN = Aebp1 PE = 1 SV = 1 | 128.3 | 435.94 | 7 | 7 | 9.40 | yes | yes |
| [TSP1_MOUSE] | Thbs1 | Thrombospondin-1 OS = Mus musculus GN = Thbs1 PE = 1 SV = 1 | 129.6 | 390.40 | 12 | 8 | 9.66 | yes | yes |
| [PCOC1_MOUSE] | Pcolce | Procollagen C-endopeptidase enhancer 1 OS = Mus musculus GN = Pcolce PE = 1 SV = 2 | 50.1 | 388.92 | 9 | 7 | 22.44 | yes | yes |
| [MATN4_MOUSE] | Matn4 | Matrilin-4 OS = Mus musculus GN = Matn4 PE = 2 SV = 1 | 68.9 | 375.75 | 13 | 7 | 21.96 | yes | yes |
| [MATN1_MOUSE] | Matn1 | Cartilage matrix protein (Matrilin-1) OS = Mus musculus GN = Matn1 PE = 2 SV = 2 | 54.4 | 372.12 | 6 | 6 | 19.40 | yes | yes |
| [EMIL1_MOUSE] | Emilin1 | EMILIN-1 OS = Mus musculus GN = Emilin1 PE = 1 SV = 1 | 107.5 | 294.76 | 5 | 4 | 7.87 | yes | yes |
| [LAMB1_MOUSE] | Lamb1 | Laminin subunit beta-1 OS = Mus musculus GN = Lamb1 PE = 1 SV = 3 | 197.0 | 281.37 | 4 | 3 | 3.47 | yes | yes |
| [SPRC_MOUSE] | Sparc | SPARC OS = Mus musculus GN = Sparc PE = 1 SV = 1 | 34.4 | 280.06 | 11 | 5 | 16.23 | yes | yes |
| [NID2_MOUSE] | Nid2 | Nidogen-2 OS = Mus musculus GN = Nid2 PE = 1 SV = 2 | 153.8 | 233.27 | 5 | 4 | 5.20 | yes | yes |
| [COMP_MOUSE] | Comp | Cartilage oligomeric matrix protein OS = Mus musculus GN = Comp PE = 1 SV = 2 | 82.3 | 203.03 | 4 | 4 | 7.55 | yes | yes |
| [TSP2_MOUSE] | Thbs2 | Thrombospondin-2 OS = Mus musculus GN = Thbs2 PE = 1 SV = 2 | 129.8 | 168.15 | 3 | 3 | 3.67 | yes | yes |
| [LAMA4_MOUSE] | Lama4 | Laminin subunit alpha-4 OS = Mus musculus GN = Lama4 PE = 1 SV = 2 | 201.7 | 160.30 | 3 | 3 | 2.92 | yes | yes |
| [NID1_MOUSE] | Nid1 | Nidogen-1 OS = Mus musculus GN = Nid1 PE = 1 SV = 2 | 136.5 | 151.10 | 3 | 3 | 5.46 | yes | yes |
| [FBLN5_MOUSE] | Fbln5 | Fibulin-5 OS = Mus musculus GN = Fbln5 PE = 1 SV = 1 | 50.2 | 127.36 | 3 | 3 | 9.15 | yes | yes |
| [FBLN2_MOUSE] | Fbln2 | Fibulin-2 OS = Mus musculus GN = Fbln2 PE = 1 SV = 2 | 131.7 | 103.63 | 2 | 2 | 2.29 | yes | yes |
| [FBLN1_MOUSE] | Fbln1 | Fibulin-1 OS = Mus musculus GN = Fbln1 PE = 1 SV = 2 | 78.0 | 95.22 | 3 | 2 | 4.96 | yes | yes |
| [IBP5_MOUSE] | Igfbp5 | Insulin-like growth factor-binding protein 5 OS = Mus musculus GN = Igfbp5 PE = 1 SV = 1 | 30.4 | 92.91 | 2 | 2 | 9.59 | yes | yes |
| [FBLN4_MOUSE] | Efemp2 | EGF-containing fibulin-like extracellular matrix protein 2 OS = Mus musculus GN = Efemp2 PE = 1 SV = 1 | 49.4 | 88.66 | 3 | 2 | 7.67 | yes | yes |
| [MATN2_MOUSE] | Matn2 | Matrilin-2 OS = Mus musculus GN = Matn2 PE = 2 SV = 2 | 106.7 | 80.75 | 1 | 1 | 2.09 | yes | |
| [LAMC1_MOUSE] | Lamc1 | Laminin subunit gamma-1 OS = Mus musculus GN = Lamc1 PE = 1 SV = 2 | 177.2 | 77.95 | 1 | 1 | 1.06 | yes | yes |
| [MATN3_MOUSE] | Matn3 | Matrilin-3 OS = Mus musculus GN = Matn3 PE = 1 SV = 2 | 51.8 | 76.56 | 1 | 1 | 6.03 | yes | yes |
| [HMCN1_MOUSE] | Hmcn1 | Hemicentin-1 (fibulin 6) OS = Mus musculus GN = Hmcn1 PE = 1 SV = 1 | 611.2 | 63.31 | 1 | 1 | 0.28 | yes | |
| [IBP7_MOUSE] | Igfbp7 | Insulin-like growth factor-binding protein 7 OS = Mus musculus GN = Igfbp7 PE = 1 SV = 3 | 29.0 | 59.65 | 1 | 1 | 4.63 | yes | |
| [VITRN_MOUSE] | Vit | Vitrin OS = Mus musculus GN = Vit PE = 1 SV = 2 | 70.7 | 55.83 | 2 | 1 | 5.38 | yes | |
| [SMOC2_MOUSE] | Smoc2 | SPARC-related modular calcium-binding protein 2 OS = Mus musculus GN = Smoc2 PE = 1 SV = 1 | 49.9 | 43.80 | 1 | 1 | 1.79 | yes | |
| Collagens | |||||||||
| [COCA1_MOUSE] | Col12a1 | Collagen alpha-1(XII) chain OS = Mus musculus GN = Col12a1 PE = 2 SV = 3 | 340.0 | 4822.72 | 137 | 82 | 37.88 | yes | yes |
| [CO1A2_MOUSE] | Col1a2 | Collagen alpha-2(I) chain OS = Mus musculus GN = Col1a2 PE = 2 SV = 2 | 129.5 | 2264.87 | 56 | 38 | 48.54 | yes | yes |
| [CO1A1_MOUSE] | Col1a1 | Collagen alpha-1(I) chain OS = Mus musculus GN = Col1a1 PE = 1 SV = 4 | 137.9 | 2013.20 | 51 | 38 | 43.15 | yes | yes |
| [CO2A1_MOUSE] | Col2a1 | Collagen alpha-1(II) chain OS = Mus musculus GN = Col2a1 PE = 1 SV = 2 | 141.9 | 1997.23 | 53 | 36 | 34.50 | yes | yes |
| [COBA1_MOUSE] | Col11a1 | Collagen alpha-1(XI) chain OS = Mus musculus GN = Col11a1 PE = 1 SV = 2 | 180.9 | 914.89 | 33 | 14 | 13.91 | yes | yes |
| [CO6A1_MOUSE] | Col6a1 | Collagen alpha-1(VI) chain OS = Mus musculus GN = Col6a1 PE = 2 SV = 1 | 108.4 | 759.85 | 18 | 11 | 15.61 | yes | yes |
| [COBA2_MOUSE] | Col11a2 | Collagen alpha-2(XI) chain OS = Mus musculus GN = Col11a2 PE = 2 SV = 3 | 171.4 | 534.18 | 27 | 12 | 9.74 | yes | yes |
| [CO9A1_MOUSE] | Col9a1 | Collagen alpha-1(IX) chain OS = Mus musculus GN = Col9a1 PE = 2 SV = 2 | 92.0 | 497.54 | 12 | 8 | 12.27 | yes | yes |
| [COEA1_MOUSE] | Col14a1 | Collagen alpha-1(XIV) chain OS = Mus musculus GN = Col14a1 PE = 2 SV = 2 | 192.9 | 448.31 | 15 | 8 | 7.29 | yes | yes |
| [CO5A1_MOUSE] | Col5a1 | Collagen alpha-1(V) chain OS = Mus musculus GN = Col5a1 PE = 2 SV = 2 | 183.6 | 424.06 | 12 | 7 | 8.60 | yes | yes |
| [CO6A2_MOUSE] | Col6a2 | Collagen alpha-2(VI) chain OS = Mus musculus GN = Col6a2 PE = 2 SV = 3 | 110.3 | 306.96 | 7 | 7 | 8.22 | yes | yes |
| [CO9A2_MOUSE] | Col9a2 | Collagen alpha-2(IX) chain OS = Mus musculus GN = Col9a2 PE = 2 SV = 1 | 65.3 | 263.90 | 5 | 4 | 8.14 | yes | yes |
| [CO3A1_MOUSE] | Col3a1 | Collagen alpha-1(III) chain OS = Mus musculus GN = Col3a1 PE = 1 SV = 4 | 138.9 | 211.05 | 5 | 5 | 5.46 | yes | yes |
| [CO4A1_MOUSE] | Col4a1 | Collagen alpha-1(IV) chain OS = Mus musculus GN = Col4a1 PE = 1 SV = 4 | 160.6 | 61.42 | 4 | 1 | 1.86 | yes | |
| [CO5A2_MOUSE] | Col5a2 | Collagen alpha-2(V) chain OS = Mus musculus GN = Col5a2 PE = 1 SV = 1 | 144.9 | 58.70 | 3 | 1 | 1.47 | yes | yes |
| [COIA1_MOUSE] | Col18a1 | Collagen alpha-1(XVIII) chain OS = Mus musculus GN = Col18a1 PE = 1 SV = 4 | 182.1 | 48.25 | 1 | 1 | 1.86 | yes | |
| [CO6A5_MOUSE] | Col6a5 | Collagen alpha-5(VI) chain OS = Mus musculus GN = Col6a5 PE = 1 SV = 4 | 289.4 | 31.88 | 1 | 1 | 0.45 | yes | yes |
| Proteoglycans | |||||||||
| [PGBM_MOUSE] | Hspg2 | Basement membrane-specific heparan sulfate proteoglycan core protein (Perlecan) OS = Mus musculus GN = Hspg2 PE = 1 SV = 1 | 398.0 | 2254.48 | 58 | 42 | 17.94 | yes | yes |
| [LUM_MOUSE] | Lum | Lumican OS = Mus musculus GN = Lum PE = 1 SV = 2 | 38.2 | 623.55 | 24 | 11 | 31.36 | yes | yes |
| [PGS1_MOUSE] | Bgn | Biglycan OS = Mus musculus GN = Bgn PE = 1 SV = 1 | 41.6 | 493.16 | 21 | 8 | 24.93 | yes | yes |
| [PGCA_MOUSE] | Acan | Aggrecan core protein OS = Mus musculus GN = Acan PE = 1 SV = 2 | 221.8 | 453.63 | 16 | 10 | 5.58 | yes | yes |
| [MIME_MOUSE] | Ogn | Mimecan OS = Mus musculus GN = Ogn PE = 1 SV = 1 | 34.0 | 401.06 | 14 | 6 | 19.80 | yes | yes |
| [HPLN1_MOUSE] | Hapln1 | Hyaluronan and proteoglycan link protein 1 OS = Mus musculus GN = Hapln1 PE = 1 SV = 1 | 40.5 | 295.58 | 7 | 6 | 18.26 | yes | yes |
| [PGS2_MOUSE] | Dcn | Decorin OS = Mus musculus GN = Dcn PE = 1 SV = 1 | 39.8 | 232.66 | 6 | 5 | 14.97 | yes | yes |
| [CSPG2_MOUSE] | Vcan | Versican core protein OS = Mus musculus GN = Vcan PE = 1 SV = 2 | 366.6 | 212.58 | 5 | 3 | 1.64 | yes | yes |
| [FMOD_MOUSE] | Fmod | Fibromodulin OS = Mus musculus GN = Fmod PE = 2 SV = 1 | 43.0 | 183.28 | 4 | 4 | 17.29 | yes | yes |
| [EPYC_MOUSE] | Epyc | Epiphycan OS = Mus musculus GN = Epyc PE = 2 SV = 1 | 36.7 | 95.30 | 1 | 1 | 5.28 | yes | yes |
| [OMD_MOUSE] | Omd | Osteomodulin OS = Mus musculus GN = Omd PE = 2 SV = 1 | 49.7 | 77.73 | 2 | 2 | 7.80 | yes | |
| [CHADL_MOUSE] | Chadl | Chondroadherin-like protein OS = Mus musculus GN = Chadl PE = 1 SV = 1 | 81.3 | 66.49 | 1 | 1 | 2.27 | yes | yes |
| [PRG4_MOUSE] | Prg4 | Proteoglycan 4 OS = Mus musculus GN = Prg4 PE = 1 SV = 2 | 115.9 | 58.62 | 1 | 1 | 1.52 | yes | yes |
| Matrisome-Associated | |||||||||
| ECM-Affiliated | |||||||||
| [CSPG4_MOUSE] | Cspg4 | Chondroitin sulfate proteoglycan 4 OS = Mus musculus GN = Cspg4 PE = 1 SV = 3 | 252.2 | 788.32 | 23 | 14 | 10.27 | yes | yes |
| [ANXA2_MOUSE] | Anxa2 | Annexin A2 OS = Mus musculus GN = Anxa2 PE = 1 SV = 2 | 38.7 | 659.62 | 16 | 11 | 43.07 | yes | yes |
| [ANXA5_MOUSE] | Anxa5 | Annexin A5 OS = Mus musculus GN = Anxa5 PE = 1 SV = 1 | 35.7 | 488.72 | 12 | 9 | 28.53 | yes | yes |
| [ANXA6_MOUSE] | Anxa6 | Annexin A6 OS = Mus musculus GN = Anxa6 PE = 1 SV = 3 | 75.8 | 274.22 | 4 | 4 | 9.36 | yes | |
| [LEG1_MOUSE] | Lgals1 | Galectin-1 OS = Mus musculus GN = Lgals1 PE = 1 SV = 3 | 14.9 | 266.61 | 17 | 5 | 34.07 | yes | yes |
| [GPC1_MOUSE] | Gpc1 | Glypican-1 OS = Mus musculus GN = Gpc1 PE = 1 SV = 1 | 61.3 | 238.48 | 3 | 3 | 11.31 | yes | |
| [ANXA1_MOUSE] | Anxa1 | Annexin A1 OS = Mus musculus GN = Anxa1 PE = 1 SV = 2 | 38.7 | 222.80 | 5 | 4 | 15.32 | yes | yes |
| [CLC11_MOUSE] | Clec11a | C-type lectin domain family 11 member A OS = Mus musculus GN = Clec11a PE = 2 SV = 1 | 36.4 | 123.68 | 2 | 2 | 9.45 | yes | yes |
| [TETN_MOUSE] | Clec3b | Tetranectin OS = Mus musculus GN = Clec3b PE = 1 SV = 2 | 22.2 | 67.39 | 2 | 1 | 5.94 | yes | |
| [CLC3A_MOUSE] | Clec3a | C-type lectin domain family 3 member A OS = Mus musculus GN = Clec3a PE = 3 SV = 1 | 22.2 | 41.91 | 1 | 1 | 10.20 | yes | yes |
| [LEG3_MOUSE] | Lgals3 | Galectin-3 OS = Mus musculus GN = Lgals3 PE = 1 SV = 3 | 27.5 | 35.01 | 1 | 1 | 4.92 | yes | yes |
| [SEM7A_MOUSE] | Sema7a | Semaphorin-7A OS = Mus musculus GN = Sema7a PE = 1 SV = 1 | 74.9 | 32.36 | 1 | 1 | 2.26 | yes | |
| ECM Regulators | |||||||||
| [SERPH_MOUSE] | Serpinh1 | Serpin H1 OS = Mus musculus GN = Serpinh1 PE = 1 SV = 3 | 46.5 | 1089.19 | 43 | 17 | 51.80 | yes | yes |
| [MMP13_MOUSE] | Mmp13 | Collagenase 3 OS = Mus musculus GN = Mmp13 PE = 1 SV = 1 | 54.1 | 1082.35 | 29 | 19 | 56.14 | yes | yes |
| [PEDF_MOUSE] | Serpinf1 | Pigment epithelium-derived factor OS = Mus musculus GN = Serpinf1 PE = 1 SV = 2 | 46.2 | 1009.46 | 36 | 17 | 49.88 | yes | yes |
| [MMP2_MOUSE] | Mmp2 | 72 kDa type IV collagenase OS = Mus musculus GN = Mmp2 PE = 2 SV = 1 | 74.1 | 432.22 | 11 | 8 | 25.83 | yes | yes |
| [CD109_MOUSE] | Cd109 | CD109 antigen OS = Mus musculus GN = Cd109 PE = 2 SV = 1 | 161.6 | 416.76 | 7 | 7 | 7.98 | yes | |
| [MMP3_MOUSE] | Mmp3 | Stromelysin-1 OS = Mus musculus GN = Mmp3 PE = 2 SV = 2 | 53.8 | 401.98 | 11 | 10 | 25.16 | yes | yes |
| [SPA3N_MOUSE] | Serpina3n | Serine protease inhibitor A3N OS = Mus musculus GN = Serpina3n PE = 1 SV = 1 | 46.7 | 252.13 | 5 | 4 | 14.83 | yes | yes |
| [CYTC_MOUSE] | Cst3 | Cystatin-C OS = Mus musculus GN = Cst3 PE = 2 SV = 2 | 15.5 | 213.65 | 5 | 4 | 37.86 | yes | yes |
| [CATS_MOUSE] | Ctss | Cathepsin S OS = Mus musculus GN = Ctss PE = 1 SV = 2 | 38.4 | 204.21 | 4 | 4 | 13.24 | yes | |
| [CATB_MOUSE] | Ctsb | Cathepsin B OS = Mus musculus GN = Ctsb PE = 1 SV = 2 | 37.3 | 170.41 | 4 | 3 | 14.16 | yes | yes |
| [ITIH1_MOUSE] | Itih1 | Inter-alpha-trypsin inhibitor heavy chain H1 OS = Mus musculus GN = Itih1 PE = 1 SV = 2 | 101.0 | 136.04 | 3 | 3 | 11.03 | yes | |
| [SPA3C_MOUSE] | Serpina3c | Serine protease inhibitor A3C OS = Mus musculus GN = Serpina3c PE = 2 SV = 1 | 46.7 | 131.55 | 5 | 1 | 9.35 | yes | yes |
| [CATD_MOUSE] | Ctsd | Cathepsin D OS = Mus musculus GN = Ctsd PE = 1 SV = 1 | 44.9 | 125.57 | 3 | 2 | 10.49 | yes | yes |
| [BMP1_MOUSE] | Bmp1 | Bone morphogenetic protein 1 OS = Mus musculus GN = Bmp1 PE = 1 SV = 2 | 111.6 | 112.07 | 1 | 1 | 1.61 | yes | |
| [ITIH2_MOUSE] | Itih2 | Inter-alpha-trypsin inhibitor heavy chain H2 OS = Mus musculus GN = Itih2 PE = 1 SV = 1 | 105.9 | 110.29 | 2 | 2 | 4.97 | yes | |
| [GDN_MOUSE] | Serpine2 | Glia-derived nexin (serpin E) OS = Mus musculus GN = Serpine2 PE = 1 SV = 2 | 44.2 | 106.05 | 2 | 2 | 8.06 | yes | |
| [A2MP_MOUSE] | A2mp | Alpha-2-macroglobulin-P OS = Mus musculus GN = A2mp PE = 2 SV = 2 | 164.2 | 80.38 | 1 | 1 | 1.49 | yes | yes |
| [CATL1_MOUSE] | Ctsl | Cathepsin L1 OS = Mus musculus GN = Ctsl PE = 1 SV = 2 | 37.5 | 77.02 | 2 | 2 | 6.59 | yes | yes |
| [ADA15_MOUSE] | Adam15 | Disintegrin and metalloproteinase domain-containing protein 15 OS = Mus musculus GN = Adam15 PE = 1 SV = 2 | 92.6 | 71.85 | 1 | 1 | 2.66 | yes | |
| [PAI2_MOUSE] | Serpinb2 | Plasminogen activator inhibitor 2, macrophage OS = Mus musculus GN = Serpinb2 PE = 2 SV = 1 | 46.3 | 64.13 | 1 | 1 | 3.37 | yes | |
| [TIMP1_MOUSE] | Timp1 | Metalloproteinase inhibitor 1 OS = Mus musculus GN = Timp1 PE = 1 SV = 2 | 22.6 | 56.58 | 1 | 1 | 4.39 | yes | yes |
| [MMP12_MOUSE] | Mmp12 | Macrophage metalloelastase OS = Mus musculus GN = Mmp12 PE = 1 SV = 3 | 54.9 | 46.86 | 1 | 1 | 2.54 | yes | |
| [TIMP2_MOUSE] | Timp2 | Metalloproteinase inhibitor 2 OS = Mus musculus GN = Timp2 PE = 1 SV = 2 | 24.3 | 41.30 | 2 | 1 | 6.82 | yes | yes |
| [ITIH3_MOUSE] | Itih3 | Inter-alpha-trypsin inhibitor heavy chain H3 OS = Mus musculus GN = Itih3 PE = 1 SV = 3 | 99.3 | 32.43 | 1 | 1 | 1.01 | yes | |
| [LYOX_MOUSE] | Lox | Protein-lysine 6-oxidase OS = Mus musculus GN = Lox PE = 1 SV = 1 | 46.7 | 30.68 | 1 | 1 | 2.68 | yes | yes |
| [LOXL3_MOUSE] | Loxl3 | Lysyl oxidase homolog 3 OS = Mus musculus GN = Loxl3 PE = 2 SV = 2 | 83.7 | 29.26 | 1 | 1 | 1.46 | yes | |
| [PAI1_MOUSE] | Serpine1 | Plasminogen activator inhibitor 1 OS = Mus musculus GN = Serpine1 PE = 1 SV = 1 | 45.1 | 27.19 | 1 | 1 | 7.71 | yes | |
*Identified in bone-conditioned media Bone-CM1, Bone-CM2, or both as indicated.