Table 2.
Demographic and clinical characteristics
| Frequency | ||||||
|---|---|---|---|---|---|---|
| Overall | Low | Moderate | High | F | χ2 | |
| M (SD) | M (SD) | M (SD) | M (SD) | |||
| DSM IV-TR Diagnosis—MDD (n) | 86 | 36 | 26 | 24 | ||
| Sex (% females) | 57.4 | 53.5 | 59.5 | 61.5 | nsa | |
| Education (years) | 15.31 (2.95) | 15.21 (2.64) | 15.39 (2.96) | 15.58 (3.38) | 0.57 | |
| Age at enrollment | 46.85 (13.31) | 46.87 (12.50) | 47.49 (13.06) | 45.92 (15.37) | 0.08 | |
| Age at onset | 26.97 (14.75) | 27.84 (16.79) | 26.89 (13.89) | 25.65 (12.57) | 0.50 | |
| Baseline HRSD | 0.42 | |||||
| Length of current MDE (weeks) | 178.54 (182.07) | 170.89 (18.23) | 225.35 (195.59) | 125.15 (152.69) | 0.22 | |
| Recurrent MDE (% yes) | 77.8 | 77.8 | 70.3 | 88.5 | 3.93b | |
| ATHF cumulative strength rating (current MDE) | 13.46 (8.85) | 14.89 (9.50) | 15.65 (8.76) | 8.16 (5.07) | 5.20* | |
| Total medication trials (current MDE) | 5.57 (2.95) | 5.86 (2.98) | 6.60 (2.93) | 3.96 (2.29) | 7.20** | |
DSM-IV-TR diagnostic and statistical manual of mental disorder IV-text revision, MDD major depressive disorder, MDE major depressive episode, ATHF antidepressant treatment history form
*p < 0.05; **p < 0.001
aChi-square tests revealed no significant differences between groups with respect to sex
bChi-square analyses revealed a significant difference between the moderate and high-frequency group on number of individuals endorsing a recurrent episode of depression, with a significantly higher proportion in the high-frequency group