Table 3.
Means and SD across groups for neurocognitive measures among patients who have completed an adequate trial of MST (>eight treatments) or per protocol
Adequate trial | Per protocol | |||||
---|---|---|---|---|---|---|
Pre | Post | Pre | Post | |||
Measure | M (SD) | M (SD) | t | M (SD) | M (SD) | t |
MoCA | 25.73 (3.63) | 25.96 (3.5) | −0.635 | 25.88 (3.78) | 26.02 (3.06) | −0.504 |
AMI-SF | 51.42 (6.89) | 41.58 (8.61) | 17.56* | 51.16 (7.4) | 40.98 (9.1) | 12.875* |
Trails A | 40 (33.3) | 34.05 (14.27) | 1.183 | 40.4 (31.52) | 36.38 (15.94) | 0.076 |
Trails B | 95.11 (67.89) | 84.88 (48.48) | −0.173 | 93.21 (66.49) | 90.64 (56.14) | −0.369 |
Symbol coding | 50.68 (13.6) | 51.09 (13.44) | 0.866 | 50.75 (13.66) | 49.05 (12.26) | 1.783 |
HVLT-R total | 25.26 (6.29) | 24.67 (5.2) | 2.059 | 25.53 (6.64) | 24.32 (5.5) | 2.399 |
HVLT-R recall | 8.78 (2.93) | 8.53 (3) | 1.661 | 8.93 (3) | 8.34 (3.33) | 2.233 |
HVLT-R recognition index | 10.53 (1.93) | 10.73 (1.66) | −0.571 | 10.8 (1.53) | 10.57 (1.82) | 1.277 |
Spatial span forward | 8.47 (2) | 8.58 (1.99) | 0.177 | 8.53 (1.85) | 8.41 (1.92) | 0.561 |
Spatial span back | 7.78 (2.06) | 7.93 (1.99) | 0.575 | 7.76 (1.92) | 7.41 (1.93) | 1.677 |
Spatial span total | 16.24 (3.64) | 16.51 (3.54) | 0.454 | 16.29 (3.22) | 15.82 (3.45) | 1.38 |
LNS total | 15 (3.85) | 14.99 (3.82) | 0.872 | 15.2 (3.73) | 14.77 (4.09) | 1.275 |
Mazes total score | 14.33 (7.91) | 15.09 (8.62) | −0.451 | 12.84 (7.55) | 13.02 (8.26) | −0.087 |
BVMT-R total | 21.8 (8.78) | 25.39 (7.41) | −3.923* | 22.6 (8.29) | 25.1 (7.73) | −2.709 |
BVMT-R learning | 3.94 (2.16) | 3.96 (2.23) | 0.307 | 3.84 (2.26) | 4 (2.18) | −0.282 |
BVMT-R recall | 8.4 (3.05) | 9.85 (2.49) | −4.318* | 8.65 (2.84) | 9.6 (2.59) | −2.506 |
BVMT-R recognition index | 5.58 (0.81) | 5.81 (0.49) | −2.114 | 5.58 (0.73) | 5.83 (0.44) | −1.939 |
COWAT total | 39.06 (14.55) | 37.47 (14.36) | 1.458 | 39.58 (16.2) | 37.1 (15.49) | 2.315 |
Categories total | 54.63 (19.4) | 51.14 (20.66) | 2.69 | 55.35 (20.89) | 53.07 (20.15) | 2.4 |
Stroop solor-word score | 95.19 (22.25) | 95.8 (22.02) | 0.493 | 95.19 (22.02) | 94.63 (22.92) | 0.299 |
Stroop color-word time (sec) | 113.62 (16.23) | 111.09 (17.92) | 2.282 | 115.4 (17.85) | 115.8 (17.3) | 0.407 |
MoCA Montreal Cognitive Assessment, AMI-SF autobiographical memory interview-short form, Trails A/B trail making test, Part A or B, HVLT-R Hopkins Verbal Learning Test-Revised, LNS letter number span, BVMT-R Brief Visuospatial Memory Test-Revised, COWAT Controlled Oral Word Association Test, Categories Category Fluency Test
*p < 0.005