Table 1.

Demographic and clinical characteristics of study participants across several time points

Study site-specific sample characteristics at baseline
Study site and scanner model	Sex	Control			MDD
		N	Mean age	SD	N	Mean age	SD
Center for Addiction and Mental Health	Females	2	28.0	7.1	8	30.4	12.1
GE 3.0 T Discovery MR750	Males	5	32.2	12.9	1	33.0	–
McMaster University	Females	12	32.8	11.2	22	33.9	12.5
GE 3.0 T Discovery MR750	Males	7	39.4	15.5	9	33.0	15.1
Queen’s University	Females	11	29.6	8.9	8	41.0	17.4
Siemens 3.0 T TrioTim	Males	3	25.0	4.0	10	43.1	13.2
Toronto General Hospital	Females	16	34.9	12.6	31	32.8	12.1
GE 3.0 T Signa HDxt	Males	7	31.4	6.3	19	40.9	11.9
University of Calgary	Females	21	33.3	11.1	18	30.3	11.7
GE 3.0 T Discovery MR750	Males	14	30.1	7.0	13	35.2	11.6
University of British Columbia	Females	8	36.1	12.7	39	32.9	11.8
Phillips 3.0 T Intera	Males	4	35.8	9.2	18	39.1	10.8
Total sample characteristics
Baseline	Sex	Control			MDD
		N	Mean age	SD	N	Mean age	SD
	Females	70	33.2	11.1	126	33.0	12.4
	Males	40	32.4	10.0	70	38.6	12.2
	Total	110	32.9	10.7	196	35.0	12.6
Week 8		Remitters			Non-remitters
	Females	35	32.1	11.4	74	33.8	12.9
	Males	18	36.9	12	45	39.3	12.3
	Total	53	33.7	11.7	119	35.8	12.9
		Responders			Non-responders
	Females	54	33	12	55	33	12
	Males	27	36.7	11	36	39.6	13
	Total	81	34.2	23	91	36	13
Week 16		Remitters			Non-remitters
	Females	63	33.6	12	36	35.1	13
	Males	33	37.9	11	26	38.5	12
	Total	96	35.1	12	62	36.5	13
		Responders			Non-responders
	Females	76	33.8	12	23	35.8	14
	Males	42	36.7	11	17	40	12
	Total	118	34.8	12	40	37.9	13

SD standard deviation, HC healthy comparison participants, MDD participants with major depressive disorder, NS non-significant