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. 2019 Dec 9;5:48. doi: 10.1186/s40798-019-0219-7

Table 4.

Summary of findings from meta-analysis describing the relationship between external load metrics of level 1 [3] and fatigue-related markers

Predictors Fatigue-related markers Time ṝ Lower CL Upper CL Number of studies/correlations Evidence n I2 chi2 p
TD Muscle damage Post 0.36 0.05 0.67 5/3 Limited 48 66 2.95 0.09
G + 24H 0.36 0.19 0.53 5/6 Limited 87 0 4.73 0.45
G + 48H 0.23 0.05 0.42 6/7 Moderate 97 0 4.81 0.44
G + 72H − 0.02 1/1 No 10
CMJPPO G + 24H − 0.16 − 0.47 0.15 2/5 Conflicted 67 41 7.83 0.10
G + 48H 0.09 − 0.08 0.27 2/5 Moderate 67 0 2.46 0.65
CMJ performance G + 48H 0.04 1/1 No 10
G + 72H − 0.06 1/1 No 10
Leucocytes count G + 24H − 0.10 2/1 No 39
G + 48H 0.21 2/1 No 39
G + 72H 0.09 2/1 No 39
Cortisol Post NS 1/0 No
G + 24H 0.50 1/1 Limited 20
G + 48H 0.52 1/1 Limited 20
Testosterone Post NS 1/1 No 20
G + 24H NS 1/1 No 20
G + 48H NS 1/1 No 20
PT 1 Hz Post − 0.19 1/1 No 19
PT 10 Hz Post − 0.20 1/1 No 19
PT 100 Hz Post − 0.17 1/1 No 19
DOMS G + 24H − 0.04 1/1 No 20
G + 48H 0.06 1/1 No 20
G + 72H 0.04 1/1 No 20
PT Concentric KE G + 24H − 0.68 1/1 Limited 20
G + 48H 0.43 1/1 Limited 20
G + 72H 0.42 1/1 Limited 20
PT Concentric KF G + 24H − 0.76 1/1 Limited 20
G + 48H 0.65 1/1 Limited 20
G + 72H 0.58 1/1 Limited 20
PT Eccentric KE G + 24H − 0.59 1/1 Limited 20
G + 48H 0.40 1/1 Limited 20
G + 72H 0.44 1/1 Limited 20
PT Eccentric KF G + 24H − 0.82 1/1 Limited 20
G + 48H 0.58 1/1 Limited 20
G + 72H 0.56 1/1 Limited 20
BAM+ G + 24H 0.09 1/1 No 35
G + 48H 0.14 1/1 No 35
TD/min Muscle damage G + 24H 0.13 0.05 0.26 2/2 Limited 67
G + 48H − 0.06 0.00 − 0.11 2/2 Limited 67
CMJPPO G + 24H − 0.03 − 0.05 − 0.01 2/2 Limited 67
G + 48H − 0.11 − 0.11 − 0.10 2/2 Limited 67
BAM+ G + 24H − 0.47 1/1 Limited 35
G + 48H − 0.51 1/1 Limited 35
HIR Muscle damage Post 0.55 0.33 0.78 5/3 Moderate 45 59 3.40 0.18
G + 24H 0.37 3/ 1 Limited 20
G + 48H 0.37 0.21 0.53 3/2 Limited 35 0 0.57 0.45
MVIC Dom G + 24H − 0.55 2/1 Limited 20
G + 48H 0.43 2/1 Limited 20
G + 72H 0.46 2/1 Limited 20
DOMS G + 24H − 0.03 2/1 No 34
G + 48H 0.00 2/1 No 34
G + 72H 0.04 2/1 No 34
Leucocytes count G + 24H − 0.11 2/1 No 39
G + 48H 0.21 2/1 No 39
Cortisol Post NS 2/0 No
G + 24H NS 1/0 No
G + 48H NS 1/0 No
Testosterone Post NS 2/0 No
G + 24H NS 1/0 No
G + 48H NS 1/0 No
PT 1 Hz Post − 0.22 1/1 No 19
PT 10 Hz Post − 0.24 1/1 No 19
PT 100 Hz Post − 0.20 1/1 No 19
PT Concentric KE G + 24H − 0.69 1/1 Limited 20
G + 48H 0.46 1/1 Limited 20
G + 72H 0.45 1/1 Limited 20
PT Concentric KF G + 24H − 0.77 1/1 Limited 20
G + 48H 0.68 1/1 Limited 20
G + 72H 0.59 1/1 Limited 20
PT Eccentric KE G + 24H − 0.59 1/1 Limited 20
G + 48H 0.43 1/1 Limited 20
G + 72H 0.46 1/1 Limited 20
PT Eccentric KF G + 24H − 0.83 1/1 Limited 20
G + 48H 0.60 1/1 Limited 20
G + 72H 0.58 1/1 Limited 20
VHIR Muscle damage Post 0.67 0.40 0.94 5/3 Moderate 45 77 8 0.02
G + 24H 0.54 0.35 0.65 5/6 Strong 87 0 2.80 0.73
G + 48H 0.36 0.19 0.53 5/7 Moderate 87 0 4.55 0.47
CMJPPO G + 24H − 0.52 − 0.64 − 0.40 2/5 Strong 67 0 2.21 0.70
G + 48H − 0.25 − 0.48 − 0.02 2/5 Limited 67 0 4.63 0.33
MVIC Dom G + 24H − 0.57 1/1 Limited 20
G + 48H 0.45 1/1 Limited 20
G + 72H 0.43 1/1 Limited 20
Leucocytes count G + 24H − 0.12 2/1 No 39
G + 48H 0.19 2/1 No 39
BAM+ G + 24H − 0.21 1/1 No 35
G + 48H − 0.17 1/1 No 35
Cortisol Post NS 2/0 No
G + 24H NS 1/0 No
G + 48H NS 1/0 No
Testosterone Post NS 2/0 No
G + 24H NS 1/0 No
G + 48H NS 1/0 No
CMJ performance Post NS 1/0 No
G + 24H NS 1/0 No
G + 48H NS 1/0 No
DOMS G + 24H 0.07 1/1 No 20
G + 48H 0.07 1/1 No 20
G + 72H − 0.10 1/1 No 20
PT Concentric KE G + 24H − 0.69 1/1 Limited 20
G + 48H 0.51 1/1 Limited 20
G + 72H 0.51 1/1 Limited 20
PT Concentric KF G + 24H − 0.78 1/1 Limited 20
G + 48H 0.72 1/1 Limited 20
G + 72H 0.61 1/1 Limited 20
PT Eccentric KE G + 24H − 0.59 1/1 Limited 20
G + 48H 0.51 1/1 Limited 20
G + 72H 0.48 1/1 Limited 20
PT Eccentric KF G + 24H − 0.83 1/1 Limited 20
G + 48H 0.63 1/1 Limited 20
G + 72H 0.62 1/1 Limited 20
VHIR dist/min Muscle damage G + 24H 0.37 0.11 0.55 2/5 Limited 67
G + 48H 0.13 0.05 0.31 2/5 Limited 67
CMJPPO G + 24H − 0.22 − 0.48 − 0.03 2/5 Limited 67
G + 48H − 0.25 − 0.53 0.05 2/5 Limited 67
BAM+ G + 24H − 0.44 1/1 Limited 35
G + 48H − 0.40 1/1 Limited 35
VHIR runs/min Muscle damage G + 24H 0.24 0.06 0.42 2/5 Limited 67
G + 48H 0.11 − 0.05 0.29 2/5 Limited 67
CMJ peak power G + 24H − 0.22 − 0.49 − 0.05 2/5 Limited 67
G + 48H − 0.20 − 0.41 − 0.02 2/5 Limited 67
Cortisol Post NS 1/1 No
Testosterone Post NS 1/1 No
BAM+ G + 24H − 0.55 1/1 Limited 35
G + 48H − 0.49 1/1 Limited 35
Sprint Muscle damage Post 0.12 2/1 Limited 35
G + 24H 0.40 2/1 Limited 35
G + 48H 0.38 3/2 Limited 45
G + 72H − 0.02 1/1 Limited 10
MVIC G + 24H − 0.51 2/1 Limited 20
G + 48H 0.35 2/1 Limited 20
G + 72H 0.35 2/1 Limited 20
Leucocyte count G + 24H − 0.10 1/1 Limited 20
G + 48H 0.17 1/1 Limited 20
G + 72H − 0.23 1/1 Limited 20
DOMS G + 24H 0.31 2/2 Limited 20
G + 48H 0.05 2/1 Limited 20
G + 72H − 0.37 2/1 Limited 20
PT Concentric KE G + 24H − 0.58 1/1 Limited 20
G + 48H 0.55 1/1 Limited 20
G + 72H 0.58 1/1 Limited 20
PT Concentric KF G + 24H − 0.70 1/1 Limited 20
G + 48H 0.70 1/1 Limited 20
G + 72H 0.56 1/1 Limited 20
PT Eccentric KE G + 24H − 0.45 1/1 Limited 20
G + 48H 0.64 1/1 Limited 20
G + 72H 0.45 1/1 Limited 20
PT Eccentric KF G + 24H − 0.68 1/1 Limited 20
G + 48H 0.63 1/1 Limited 20
G + 72H 0.61 1/1 Limited 20
CMJ performance Post NS 2/0 No
G + 24H NS 2/0 No
G + 48H 0.27 3/1 No 10
G + 72H 0.27 3/1 No 10
TQR G + 24H NS 1/0 No
G + 48H NS 1/0 No
G + 72H NS 1/0 No

ṝ : pooled correlation from Hunter and Schmidt random-effects method, CL: confidence limit, N: number of players, TD: total distance, KE: knee extension, KF: knee flexion, CMJ: countermovement jump, CMJPPO: countermovement jump peak power, PT: peak torque, DOMS: delayed onset muscle soreness, BAM+: brief assessment of the mood, HIR: high-intensity running (> 4 m s−1), MVIC: maximal voluntary isometric contraction, VHIR: very high-intensity running (> 5.5 m s−1), conc: concentric, ecc: eccentric, Acc: acceleration, Decel: deceleration, No: no evidence, NS: not specified, PT 1–100 Hz: peak torque induced by single (1 Hz) and paired electrical stimuli (10 and 100 Hz)