TABLE 2.
Comparison of T-lymphocyte subtypes, humoral immunity and cytokines between bacterial co-infection group and pneumonia severity group.
| Survival group | Overall death | p | Non-bacteria | Co-bacteria | p | |
| T lymphocytes | ||||||
| CD3 + (%) | 68.62 ± 12.63 | 61.29 ± 17.67 | <0.001 | 68.57 ± 13.06 | 64.60 ± 15.27 | 0.020 |
| CD4 + (%) | 40.03 ± 11.19 | 34.14 ± 14.16 | 0.001 | 39.67 ± 11.56 | 37.54 ± 12.70 | 0.149 |
| CD8 + (%) | 26.01 ± 10.74 | 24.07 ± 15.54 | 0.271 | 26.04 ± 11.80 | 24.85 ± 11.43 | 0.409 |
| CD3 absolute count | 975.35 ± 662.75 | 530.34 ± 426.76 | <0.001 | 1002.81 ± 644.67 | 666.09 ± 602.81 | <0.001 |
| CD4 absolute count | 466.40 ± 333.71 | 256.41 ± 191.23 | <0.001 | 468.47 ± 318.11 | 344.52 ± 320.07 | 0.008 |
| CD8 absolute count | 328.07 ± 208.02 | 223.37 ± 231.10 | 0.006 | 339.19 ± 208.94 | 245.02 ± 216.68 | 0.003 |
| CD4 + /CD8 + Ratio | 1.88 ± 1.09 | 1.99 ± 1.38 | 0.536 | 1.89 ± 1.09 | 1.91 ± 1.25 | 0.940 |
| Cytokine | ||||||
| IL-1 | 5.69 ± 2.59 | 7.25 ± 8.34 | 0.092 | 6.19 ± 5.41 | 5.95 ± 3.73 | 0.763 |
| IL-2R | 1290.12 ± 1145.35 | 1899.69 ± 1323.24 | 0.009 | 1194.46 ± 1031.01 | 1732.77 ± 1353.35 | 0.008 |
| IL-6 | 32.83 ± 74.75 | 136.22 ± 215.29 | <0.001 | 24.74 ± 45.68 | 95.94 ± 178.97 | 0.001 |
| IL-8 | 120.51 ± 291.26 | 207.67 ± 310.19 | 0.131 | 115.26 ± 185.37 | 173.91 ± 392.94 | 0.239 |
| IL-10 | 11.12 ± 12.14 | 16.58 ± 15.72 | 0.033 | 9.70 ± 10.39 | 15.81 ± 15.51 | 0.005 |
| TNF-α | 15.59 ± 14.53 | 14.97 ± 10.77 | 0.828 | 15.06 ± 14.65 | 15.85 ± 12.62 | 0.749 |
The bolded values are p-values < 0.05, which represent significant differences between subgroups.