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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Curr Opin Immunol. 2019 Sep 26;61:69–73. doi: 10.1016/j.coi.2019.08.005

Figure 1. Genetically engineered T cell therapeutic strategies for autoimmune disease.

Figure 1.

Chimeric autoantibody receptor (CAAR) T cells for antigen-specific B cell depletion, anti-peptide:MHC CAR T cells for autoreactive APC depletion, peptide:MHC immunoreceptor T cells for autoreactive T cell depletion and CAR- or TCR-Tregs for autoimmune B or T cell suppression are depicted. Figure created using BioRender.