FIGURE 8.

Distribution of energy percentiles for correctly modeled positions. “Energy percentile” refers to the percentile of the average total Rosetta energy of the correctly modeled side chain compared to that of all other side chains modeled by the design method at that position. Energy percentile was calculated for consensus (entropy ≤0.67) positions for which a method modeled the consensus at least once. A, Distribution of energy percentiles. Count n indicates the number of positions for which each method modeled the consensus side chain at least once. B, Energy percentiles as a function of design frequency are shown as boxplots. Values from (A) are binned by design frequency (low: frequency ≤ 0.33, medium: 0.33 < frequency ≤ 0.67, and high: frequency > 0.67). The number of values in each bin is shown on each boxplot. The median of the distributions is marked with a horizontal line. Second and third quartiles are marked by the box, and the whiskers extend to 1.5 times the inter-quartile range