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. Author manuscript; available in PMC: 2020 Dec 9.
Published in final edited form as: Biomacromolecules. 2019 Nov 5;20(12):4407–4418. doi: 10.1021/acs.biomac.9b01073

Figure 1.

Figure 1.

(a) Chemical structure of the azido-derivative of chain transfer agent (Az-CTPA) and radical initiator (Az-ACVA) for RAFT polymerization. (b) Synthetic scheme and characterization of the amphiphilic polymer library. (c) Zeta potential and hydrodynamic diameter of the amphiphilic polymers. N = 3. The amphiphilic polymers were formulated with 10 mol% (vs. PDS units) of dithiothreitol to form the polymeric assemblies. (d) HeLa cell viability evaluation with amphiphilic polymers at different dosage. N = 4. In each figure, error bars represent the standard deviation of replicates. (e) Synthetic scheme of the orthogonal end-group labeling strategy for amphiphilic polymers.