Figure 4.

UL51 deletions show similar UL51-dependent cell-to-cell spread defects. Confluent Vero or UL51 complementing cell monolayers were infected at low multiplicity with wild-type (black circles) UL51Δ73–244 (open circles) or UL51Δ167–244 (gray squares), and after two days of incubation in the presence of neutralizing antibody, plaques were immunostained, and plaque areas measured. Statistical significance of differences between samples was measured using one-way ANOVA and Fisher’s least significant difference test.