Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 26;10:1520. doi: 10.3389/fpls.2019.01520

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Fanani, Fukushima, Sawai, Tang, Ishimori, Sudo, Ohyama, Seki, Saito and Muranaka

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Model of the C-30 product regioselectivity. (A) In silico mutagenesis of CYP72A63^L149V/L398G. These models show CYP72A63 and CYP72A63^L149V/L398G focusing on amino acid residues #149 and #398. The red dashed line indicates the effects of amino acid substitution on active site volume. All amino acid residues are shown. (B) Illustration of potential binding modes of β-amyrin. Carbon atom positions for C-21, C-29, and C-30 in the three-dimensional structure of β-amyrin are indicated. Potential rotation of β-amyrin is indicated by the red dashed line. The distance of C-30 from the heme iron is indicated by gray dashed line.