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. 2019 Nov 26;10:1199. doi: 10.3389/fgene.2019.01199

Table 1.

Participant demographics and Medication use.

Cases (n = 89) Controls (n = 105) Total sample (n = 194) Statistical test (p value for χ2 or t-test: cases vs. controls)
% Female 89.9 84.8 87.1 p = .57
Age: mean (sd) 30.0 (11.2) 35.0 (12.9) 32.7 (12.4) p = .005
Current antidepressant (n; %)
Fluoxetine 3 (3.4%) 20 (19.0%) 23 (11.3%)
Citalopram or escitalopram 11 (14.3%) 32 (30.4%) 43 (22.2 %)
Sertraline 15 (16.9%) 13 (13.7%) 28 (14.4%)
Paroxetine 0 (0%) 3 (2.9%) 3 (1.5%)
Venlafaxine 23 (25.8%) 23 (21.9%) 46 (23.7%)
Other/unknown1 7 (7.9%) 2 (2.0%) 9 (4.6%)
Tricyclic2 9 (9.0%) 2 (2.0%) 11 (5.7%)
No antidepressant 21 (23.9%) 7 (6.9%) 28 (14.4%)
Any antidepressant 68 (76.4%) 96 (91.4%) 164 (84.5%)
Current other drugs (n, %)
Mood stabilizer3 3 (3.4%) 9 (8.6%) 9 (4.6%) .13
Antipsychotic4 12 (13.5%) 15 (14.3%) 27 (13.9%) .87
Sedative/hypnotic5 24 (27.0%) 17 (16.2%) 43 (22.2%) .07

1Mirtazapine (five cases, two controls), St John’s Wort (one case), bupropion (one case).

2Amitriptyline (three cases), nortriptyline (five cases, one control), clomipramine (one case).

3Lithium or valproate.

4Quetiapine (10 cases, 10 controls), olanzapine (0 cases, 2 controls), aripiprazole (1 case, 1 control), risperidone (1 case, 2 controls).

5Benzodiazepines, gabapentin, pregabalin or zopiclone.