Table 3.
Common biological processes shared between M. truncatula and H. sapiens as resulted from the network-based approach involving the M. truncatula network construction. The ID corresponding to each GO term (GO ID) along with putatively target genes and corresponding miRNAs are provided.
| Biological process | M. truncatula | H. sapiens | ||||
|---|---|---|---|---|---|---|
| GO ID | Gene | miRNA | GO ID | Gene | miRNA | |
| Exocytosis | GO:0006887 | Medtr4g102120 | mtr-miR5559-3p | GO:0006887 | SNPH | mtr-miR399t-5p |
| Medtr8g023330 | mtr-miR5558-3p | GO:0006904 | RIMS3 | mtr-miR482-5p | ||
| SYT1 | mtr-miR5211 | |||||
| SYT2 | mtr-miR2640 | |||||
| NOTCH1 | mtr-miR5266 | |||||
| RAB3GAP1 | mtr-miR5209 | |||||
| RPH3AL | mtr-miR2589 | |||||
| SYT15 | mtr-miR166d | |||||
| DNA replication, transcription, and modifications | GO:0006261 | Medtr4g106540 | mtr-miR5741a | GO:0090329 | INO80 | mtr-miR399t-5p |
| GO:0090329 | GO:2000104 | LIG3 | mtr-miR5294a | |||
| GO:0006268 | HMGA1 | mtr-miR5276 mtr- | ||||
| GO:0044030 | GRHL2 | miR2589 | ||||
| GO:2000678 | PER2 | mtr-miR169k | ||||
| GO:0032786 | SIN3A | mtr-miR156b-3p | ||||
| BRD4 | mtr-miR5266 | |||||
| Amino acid activation and transport | GO:0043038 | Medtr7g083030 | mtr-miR2657 | GO:0009081 | BCKDK | mtr-miR5273 |
| GO:0043039 | GO:0009083 | IVD | mtr-miR2640 | |||
| GO:0006418 | GO:0051955 | PER2 | mtr-miR169k | |||
| GO:0051957 | RAB3GAP1 | mtr-miR5209 | ||||
| GO:0009065 | NTSR1 | mtr-miR408-3p | ||||
| TINAGL1 | mtr-miR166d | |||||
| NANOS2 | mtr-miR160c | |||||
| PRODH | mtr-miR169d-3p | |||||
| RNA related processes | GO:0016071 | Medtr3g077320 | mtr-miR2629f | GO:0050686 | CELF1 | mtr-miR2670f |
| GO:0006397 | GO:0006376 | CELF2 | mtr-miR399t-5p | |||
| GO:0008380 | GO:0061014 | GIGYF2 | mtr-miR166d | |||
| GO:0000375 | GO:0061157 | TNRC6B | mtr-miR5211 | |||
| GO:0000377 | GO:0050686 | KHSRP | mtr-miR398b | |||
| GO:0000398 | MEX3D | mtr-miR2673a | ||||
| RNPS1 | mtr-miR398b | |||||
| SUPT5H | ||||||
| Histone modification | GO:0016570 | Medtr1g086590 | mtr-miR395e | GO:0043981 | KANSL1 | mtr-miR482-5p |
| GO:0016573 | Medtr4g108080 | mtr-miR156a | GO:0043982 | |||
| Protein modifications | GO:0043543 | Medtr1g086590 | mtr-miR395e | GO:0018345 | CLIP3 | mtr-miR527 |
| GO:0006473 | GO:0006517 | ZDHHC18 | mtr-miR168b | |||
| GO:0006475 | GO:0036507 | MARCH6 | mtr-miR390 | |||
| GO:0018394 | GO:0036508 | UGGT1 | mtr-miR5270a | |||
| GO:0018393 | GO:0042532 | NF2 | mtr-miR5206b | |||