Table 4.
Biological processes related to DNA repair, recombination, replication and chromatin remodeling common to A. thaliana and H. sapiens as resulted from the network-based approach. The ID corresponding to each GO term (GO ID) along with putatively target genes and corresponding miRNAs are provided.
| Biological process | A. thaliana | H. sapiens | ||||
|---|---|---|---|---|---|---|
| GO ID | Gene | miRNA | GO ID | Gene | miRNA | |
| DNA repair | GO:0006284 | DME | mtr-miR2086-3p | GO:2000779 | FOXM1 | mtr-miR169d-3p |
| GO:0045003 | DML1 | mtr-miR2651 | PPP4C | mtr-miR169k | ||
| GO:0000724 | AT1G75230 | mtr-miR5240 | ||||
| RAD54 | mtr-miR172c-5p | |||||
| RECA1 | mtr-miR5558-3p | |||||
| ASF1B | mtr-miR1509a-3 | |||||
| GMI1 | pmtr-miR169l-3p | |||||
| KU80 | mtr-miR5272f | |||||
| DNA recombination and replication | GO:0006310 | ASF1B | mtr-miR1509a-3p | GO:0090329 | INO80 | mtr-miR399t-5p |
| GMI1 | mtr-miR169l-3p | GO:2000104 | LIG3 | mtr-miR5294a | ||
| KU80 | mtr-miR5272f | GO:2000678 | PER2 | mtr-miR169k | ||
| RAD54 | mtr-miR172c-5p | GO:0032786 | SIN3A | mtr-miR156b-3p | ||
| RCK | mtr-miR5754 | BRD4 | mtr-miR5266 | |||
| RECA1 | mtr-miR5558-3p | |||||
| RPA70B | mtr-miR2592a-5p | |||||
| Chromatin remodeling | GO:0006306 | DME | mtr-miR2086-3p | GO:0043981 | KANSL1 | mtr-miR482-5p |
| GO:0044728 | DML1 | mtr-miR2651 | GO:0043982 | HMGA1 | mtr-miR5276 | |
| GO:0006305 | DRD1 | mtr-miR2650 | GO:0070828 | TNRC18 | mtr-miR2589 | |
| GO:0006304 | EMB2770 | mtr-miR7696c-5p | GO:0031507 | GRHL2 | mtr-miR2589 | |
| GO:0031056 | SDG14 | mtr-miR2650 | GO:0031936 | PHF2 | mtr-miR160c | |
| GO:0031058 | mtr-miR2086-3p | GO:0006268 | SIN3A | mtr-miR156b-3p | ||
| GO:0031060 | mtr-miR7696c-5p | GO:0044030 | ZNF304 | mtr-miR166e-5p | ||
| GO:0031062 | GO:0031935 | |||||
| GO:1905269 | GO:0031937 | |||||
| GO:1902275 | ||||||
| GO:0080188 | ||||||