Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 26;10:2707. doi: 10.3389/fimmu.2019.02707

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Jiang, Wang, Liang, Nie, Chang, Xue, Li and Min.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of MMI-0100 treatment in LPS induced the activation of microglia and astrocytes. (A) Representative confocal images of mice administered with the vehicle saline, LPS, or LPS + MMI-0100 are shown. Hippocampal histology sections were double-labeled for CD11b+ (green) and DAPI (blue) or GFAP (red) and DAPI (blue), and assessments were made with immunofluorescence microscopy, scale bars = 100 μm, 200×. (B,C) The quantification of GFAP-positive astrocytes and CD11b-positive microglia is described. Data are mean ± SEM (n = 5 mice per group). Data were analyzed using one-way ANOVA followed by Bonferroni's post-hoc test. **p < 0.01 and ***p < 0.001 compared with control. ^#p < 0.05 and ^##p < 0.01 compared with the LPS group.