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. 2019 Nov 26;9:1256. doi: 10.3389/fonc.2019.01256

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Copyright © 2019 Goldman, Waterhouse, George, O'Dwyer, Bhore, Banerjee, Lyons, Louis, Ong and Kelly.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Change in total length of target lesions from baseline up to initial progression for individual patients in concurrent cohort (dose-finding and expansion parts; A) and delayed cohort (dose-finding part only; B).